Pancreatic panniculitis in male systemic lupus erythematosus
Keywords:
Pancreatic panniculitis, azathioprine, pancreatic disease, SLEAbstract
Pancreatic panniculitis is a rare subtype of panniculitis which is associated with pancreatic disease. We report a case of a 34-year-old male with a history of systemic lupus erythematosus (SLE) complicated with proliferative lupus nephritis on maintenance azathioprine (AZA) who developed painful red nodules on the lower legs. He denied any symptom of pancreatitis. The histopathology showed subcutaneous lobular fat necrosis with anuclear adipocytes and granular deposits of calcium, consistent with pancreatic panniculitis. The investigations showed elevated lipase and amylase and the computed tomography of the abdomen revealed pancreatic pseudocyst. When AZA was discontinued in our patient, the level of lipase and amylase were decreased by half supporting the hypothesis of AZA-induced pancreatitis apart from the underlying SLE itself.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น