A case report of neutrophilic fixed drug eruption
Keywords:
neutrophilic fixed drug eruption, fixed drug eruption, mefenamic acidAbstract
Neutrophilic fixed drug eruption is a rare histopathological finding of fixed drug eruption (FDE). Whether it is a new entity or an early phase of FDE requires further investigation. We report a 34-year-old Thai female presented with multiple well-demarcated oval pruritic erythematous patches with dusky violaceous to brownish hue in the center on face, trunk and thigh. The rashes were aggravated by mefenamic acid ingestion, and improved by drug cessation. Histologic findings revealed large amount of pigmentary incontinence, also perivascular and interstitial infiltration with neutrophils and lymphohistocytes. To our knowledge, this is the first report of neutrophilic fixed drug reaction caused from mefenamic acid ingestion.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
