Toxic epidermal necrolysis-like lupus erythematosus: A case report
Keywords:
Toxic epidermal necrolysis, lupus erythematosus, epidermal necrolysisAbstract
Toxic epidermal necrolysis-like lupus erythematosus, a rare variant of cutaneous lupus erythematosus is characterized by sheet-like desquamation of the skin predominating on photo-distributed area. Clinically, the lesions can present similar to classical toxic epidermal necrolysis. This condition is complicated to be diagnosed due to the rarity of the disease and less information.
We report a case of 32-year-old Thai woman who has had a long-standing history of systemic lupus erythematosus. The patient presented with a 2-month history of developing widespread, targetoid, red to violaceous photosensitive rash, which then progressed to sheet-like desquamation predominating on sun-exposed area. Histopathology and direct immunofluorescence are compatible with lupus erythematosus. The patient was diagnosed as TEN-like LE. She was prescribed high dosage of intravenous corticosteroid and other immunosuppressive drugs, together with hydroxychloroquine. She responded well to the treatment within a few days.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
