Discrete papular mucinosis: A rare subtype of lichen myxedematosus
Keywords:
lichen myxedematosus, papular mucinosis, skin-colored papulesAbstract
Lichen myxedematosus is a chronic, progressive idiopathic cutaneous mucinosis characterized by localized or generalized papular eruption of unknown etiology in which mucin deposition in the dermis is the distinctive histologic feature. The classification system was revised into three clinicopathological subsets, localized lichen myxedematosus, scleromyxedema and atypical forms of lichen myxedematosus. We report a rare subtype of lichen myxedematosus, discrete papular subtype, presented with papular eruption on the back, chest, face and neck. Histopathology showed focal mucin accumulation in upper and mid reticular dermis with scattered stellate fibroblasts among mucinous material, confirmed by Alcian blue staining. Her serum protein electrophoresis showed polyclonal immunoglobulin, serology for hepatitis C and HIV were negative and her thyroid function test was normal. She was diagnosed with localized forms of lichen myxedematosus, discrete papular subtype and was treated with an excellent response to topical corticosteroids and oral hydroxychloroquine combination therapy.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
