Safety and efficacy of the combined use of a facial cleanser and moisturizers containing pseudo-ceramide and a eucalyptus extract for Thai non-oily sensitive skin
Keywords:
lactic acid stinging test, barrier function, ceramide, sensitive skin, ThailandAbstract
Background: In Thailand, many people feel irritation or itching in the sunshine and when they sweat, making them feel that their skin is sensitive.
Objective: To confirm the safety and the efficacy of a combination facial skincare regimen with a weakly acidic well foamed mild facial skin cleanser and moisturizers (lotion and cream) containing pseudo-ceramide and a eucalyptus extract on reducing skin symptoms of Thai non-oily sensitive facial skin.
Methods: We performed a 4-week clinical trial of facial care on 27 Thai females who have sensitive skin with normal or decreased levels of facial sebum. Each subject washed her face with a well foamed cleanser followed by application of an aqueous lotion with a eucalyptus extract and a moisturizing cream containing pseudo-ceramide and a eucalyptus extract twice a day for a total of 4 weeks. Prior to and following the 4 weeks of usage, the skin conditions of each subject were evaluated.
Results: Following 4 weeks of the combination skincare, redness, scaling, and acne were significantly improved. Accompanying those improvements, both skin hydration and cutaneous barrier function improved significantly. A lactic acid sting test indicated a significant decrease in skin sensitivity. No adverse events due to the test samples were observed. The subjects recognized the changes in their skin conditions.
Conclusion: The combination usage of a mild foaming cleanser and an aqueous lotion and moisturizing cream containing pseudo-ceramide and a eucalyptus extract is safe and may be effective for the care of sensitive skin in Thai subjects.
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