Safety and efficacy of the combined use of a facial cleanser and moisturizers containing pseudo-ceramide and a eucalyptus extract for Thai oily sensitive skin
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Keywords:
lactic acid stinging test, barrier function, ceramide, sensitive skin, ThailandAbstract
Background: In Thailand, many people recognize their skin as being sensitive. Sebum is the major factor that induces skin sensitivity and acne, and mild cleansing to remove sebum is recommended for skin care.
Objective: To confirm the safety and the efficacy of a combination facial skincare regimen with a weakly acidic foaming facial skin cleanser and moisturizers (lotion and gel) containing pseudo-ceramide and a eucalyptus extract on reducing skin symptoms of Thai oily sensitive facial skin.
Methods: We performed a 4-week clinical trial of facial care on 27 Thai females who have oily sensitive skin selected by a lactic acid stinging test. Each subject washed her face with a weakly acidic foaming cleanser and applied an aqueous lotion with a eucalyptus extract and a moisturizing gel containing pseudo-ceramide and a eucalyptus extract twice a day. Prior to and following 4 weeks of usage, the skin conditions of each subject were evaluated.
Results: After 4 weeks of the combination care, redness and acne were significantly improved, although there were no changes in the sebum secretion rate. Accompanying those improvements, both the water holding capacity and the cutaneous barrier function of the stratum corneum were significantly enhanced and skin sensitivity, indicated by a lactic acid stinging test, decreased significantly. No adverse events due to the test samples were observed and the subjects recognized the changes in their skin conditions.
Conclusion: The combination usage of a weakly acidic foaming cleanser and an aqueous lotion and moisturizing gel containing pseudo-ceramide and a eucalyptus extract is safe and may be effective for the care of oily sensitive skin in Thai subjects.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
