Coexistence of juvenile xanthogranuloma and diffuse plane xanthoma in 22-month-old boy could potentially be caused by digenic inheritance of APOB and APOE4 polymorphism

Authors

  • Kamonrat Sunantawanich INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND
  • Niorn Boonpuen INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Narumon Densupsoontorn DEPARTMENT OF PEDIATRICSFACULTY OF MEDICINE SIRIRAJ HOSPITAL, BANGKOK, THAILAND.
  • Vip Viprakasit DEPARTMENT OF PEDIATRICSFACULTY OF MEDICINE SIRIRAJ HOSPITAL, BANGKOK, THAILAND.
  • Pimpa Tantanasrigul INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND
  • Poonnawis Sudtikoonaseth INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND
  • Vesarat Wessagowit INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND

Keywords:

juvenile xanthogranuloma, diffuse plane xanthoma, dyslipidemia

Abstract

SUNANTAWANICH K*, BOONPUEN N*, DENSUPSOONTORN N**, VIPRAKASIT V**, TANTANASRIGUL P*, SUDTIKOONASETH P*, WESSAGOWIT V*. COEXISTENCE OF JUVENILE XANTHOGRANULOMA AND DIFFUSE PLANE XANTHOMA IN 22-MONTH-OLD BOY COULD POTENTIALLY BE CAUSED BY DIGENIC INHERITANCE OF APOB AND APOE4 POLYMORPHISM. THAI J DERMATOL 2020; 36: 25-30.

*INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.

**DEPARTMENT OF PEDIATRICSFACULTY OF MEDICINE SIRIRAJ HOSPITAL, BANGKOK, THAILAND.          

The coexistence of juvenile xanthogranuloma and diffuse plane xanthoma is considered a rare phenomenon. We report a 22-month-old boy with multiple orange-tan papules and yellow plaques on his entire body for 18 months. Two types of histological findings confirmed the diagnosis of juvenile xanthogranuloma and plane xanthoma, respectively. Additionally, the patient’s blood test showed high cholesterol level, which could be associated with familial or secondary dyslipidemia.

References

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Published

2020-03-18

How to Cite

Sunantawanich, K., Boonpuen, N., Densupsoontorn, N., Viprakasit, V., Tantanasrigul, P., Sudtikoonaseth, P., & Wessagowit, V. (2020). Coexistence of juvenile xanthogranuloma and diffuse plane xanthoma in 22-month-old boy could potentially be caused by digenic inheritance of APOB and APOE4 polymorphism. Thai Journal of Dermatology, 36(1), 25–30. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/223030

Issue

Vol. 36 No. 1 (2020): January - March

Section

Case Report

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