A progressive erythematous plaque on the central face and nose after mesotherapy, an uncommon presentation of Mycobacterium marinum infection
Keywords:
Mycobacterium marinum infection, Cosmetic procedures, Facial infectionAbstract
CHUMSAENGSRI C, BOONPUEN N. A PROGRESSIVE ERYTHEMATOUS PLAQUE ON THE CENTRAL FACE AND NOSE AFTER MESOTHERAPY, AN UNCOMMON PRESENTATION OF MYCOBACTERIUM MARINUM INFECTION. THAI J DERMATOL 2020; 36: 31-37.
INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
Mycobacterium marinum is a slowly growing photochromogenic nontuberculous mycobacterium and its ability to cause localized skin and soft tissue infections in individuals with exposure to contaminated freshwater or salt water. So far, only small amount cases of M. marinum infection on the face have been reported worldwide and all cases have been linked to aquatic exposure. No previous documented history of cosmetic procedures related to M. marinum facial infection. We reported a case 32-year-old Thai female who presented with atypical infected site of multiple erythematous indurated plaques on predominately central face from M. marinum infection suspected from mesotherapy. Diagnosis was made by using polymerase chain reaction (PCR) technique from skin biopsy. She was treated with clarithromycin plus ciprofloxacin for 2 months then switched to azithromycin plus ethambutol for 7 months due to pregnancy. After total 9-month therapeutic treatment, the lesions healed gradually without scar.
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