The scalp nodules as the presenting symptom of primary localized cutaneous nodular amyloidosis:A rare case report

Authors

  • Tanaporn Borriboon INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Junjira Sawasdipong INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.

Keywords:

nodular amyloidosis, primary localized cutaneous amyloidosis, scalp nodules

Abstract

BORRIBOON T, SAHAKARO C, SAWASDIPONG J, SUDTIKOONASETH P. THE SCALP NODULES AS THE PRESENTING SYMPTOM OF PRIMARY LOCALIZED CUTANEOUS NODULAR AMYLOIDOSIS: A RARE CASE REPORT. THAI J DERMATOL 2020;36:67-72.

INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.

Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare variant of primary cutaneous amyloidosis which is characterized by a single or multiple yellowish waxy nodule with telangiectasias. The predilection site is the acral area but there are some reports presenting on the head and neck regions. Amyloid protein deposition in nodular amyloidosis originates from immunoglobulin light chains secreted by plasma c ells infiltrating the skin.  We hereby report  a case of  68-year-old women presented  with multiple

waxy skin-colored to yellowish nodules on the scalp for 2 years which prior suspected of nevus sebaceous. The incisional biopsy was done.

Histopathologic findings revealed nodular deposits of amorphous eosinophilic material in the entire dermis. The Congo red stain was positive for amyloid. The patient underwent exhaustive systemic evaluations, which were all negative. According to these finding, the diagnosis of primary localized cutaneous nodular amyloidosis was made. The patient was advised to undergo long term follow-up to monitor for potential progression to systemic disease.

References

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Published

2020-06-16

How to Cite

Borriboon, T., & Sawasdipong, J. (2020). The scalp nodules as the presenting symptom of primary localized cutaneous nodular amyloidosis:A rare case report. Thai Journal of Dermatology, 36(2), 67–72. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/226775

Issue

Vol. 36 No. 2 (2020): April - June

Section

Case Report

License

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