A Presentation of Chancre Redux in An HIV-Infected Patient

Authors

  • Ya-Nin Nokdhes DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, BANGKOK, THAILAND.
  • Chalermkwan Apinuntham DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, BANGKOK, THAILAND.
  • Apiwat Chantaramanee DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, BANGKOK, THAILAND.
  • Sukhum Jiamton DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, BANGKOK, THAILAND.

Keywords:

Chancre redux, monorecidive syphilis, syphilis in HIV

Abstract

Syphilis has been a major challenge in dermatology due to its various presentations and the fact that it’s a great imitator of multiple diseases. One of the cutaneous manifestations occurring in the primary stage is typically described as a solitary, painless, clean-based ulceration with elevated border. Here by, we report a case of syphilis with genital ulcer in an HIV-infected patient after receiving treatment. Chancre redux from inadequate treatment or recurrent infection should be included in the differential diagnosis. Occasionally, a cutaneous lesion of syphilis appears with an atypical character, especially in immunocompromised patient. In this situation, differential diagnosis should be carefully made, because mistaken medical assumptions could easily happen.

References

Syphilis Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention [updated 4 June; cited 2020 2 November]. Available from: https://www.cdc.gov/std/tg2015/syphilis.htm.

Seña AC, Zhang X-H, Li T, et al. A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy. BMC Infectious Diseases 2015;15:479.

Thienkrua W, van Griensven F, Mock PA, Dunne EF, Raengsakulrach B, Wimonsate W, et al. Young Men Who Have Sex with Men at High Risk for HIV, Bangkok MSM Cohort Study, Thailand 2006-2014. AIDS Behav 2018;22:2137-46.

Leeyaphan C, Jiamton S, Prasertworonun N, Maneeprasopchoke P, Omcharoen V. Clinical and epidemiological characteristics of patients with syphilis: 5 year-case study from Thailand. J Med Assoc Thai 2014;97:963-8.

Centers for Disease Control and Prevention (CDC). HIV and syphilis infection among men who have sex with men--Bangkok, Thailand, 2005-2011. MMWR Morb Mortal Wkly Rep 2013;62:518-20.

Sewon K MA, Anna LB, Alexander HE, David JM, Amy JM, et al. . Fitzpatrick's dermatology 9th ed. New York: McGraw-Hill Education; 2019.

Steiner A, Battegay M, Greminger P, Lüthy R. HIV-Infektion und Lues. Fallbeschreibung und Literaturübersicht [HIV infection and syphilis. Case description and literature review]. Schweiz Med Wochenschr 1991;121:67-71.

Stokes Jh, Beerman H, Ingraham NR. Modern clinical syphiology. 3rd end. Philadelphia: WB Saunders, 1946;646.

Zetola NM, Klausner JD. Syphilis and HIV infection: an update. Clin Infect Dis 2007; 44: 1222-8.

Dombrowski JC, Celum C, Baeten J. Syphilis. The Travel and Tropical Medicine Manual 2017;535-44.

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Published

2021-08-17

How to Cite

Nokdhes, Y.-N., Apinuntham, C., Chantaramanee, A., & Jiamton, S. (2021). A Presentation of Chancre Redux in An HIV-Infected Patient. Thai Journal of Dermatology, 37(3), 133–8. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/243765

Issue

Vol. 37 No. 3 (2021): July - September

Section

Challenging case

License

เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

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