Effect of Different Shampoos and Contact Time on Microsporum canis Infected Hair: In vitro Model Study

Authors

  • Sumanas Bunyaratavej DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Rungsima Kiratiwongwan DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Panittra Suphatsathienkul DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Kanyalak Munprom DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Lalita Matthapan DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Salisa Supcharoenkul DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Kamonpan Lertrujiwanit DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Waranyoo Prasong DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.
  • Charussri Leeyaphan DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL, MAHIDOL UNIVERSITY, THAILAND.

Keywords:

Tinea capitis, Microsporum canis, zinc pyrithione shampoo, selenium sulfide

Abstract

Background: Tinea capitis is commonly caused by Microsporum canis. The standard treatment is systemic antifungal medications with adjunctive use of an antifungal shampoo. The current information about the effect of shampoos is limited.

Objectives: To compare the effects of different shampoos and contact times on M. canis infected hair.

Methods: This in vitro study was conducted at the Mycology Laboratory in a tertiary hospital, Thailand, in 2020. Hair taken from a child was disinfected and incubated with an M. canis colony for 15 days before divided into ten groups. Each of these samples was then mixed with distilled water, a commercial shampoo, a ketoconazole shampoo, a selenium sulfide shampoo, or a zinc pyrithione shampoo for either 2 or 5 minutes. Those samples and control-group samples were cultured for 7 days before fungal growth areas were collected and analyzed.

Results: At Day 3, the fungal colony growth areas on the samples mixed with commercial shampoo, ketoconazole shampoo, selenium sulfide shampoo, and zinc pyrithione shampoo were significantly smaller than that of the control. Moreover, the samples mixed with ketoconazole shampoo, selenium sulfide shampoo, and zinc pyrithione shampoo demonstrated a statistically different fungal-growth area from the control at Day 7. However, the duration of mixing resulted in similar areas of fungal growth for all samples.

Conclusions: Shampoos containing zinc pyrithione and commercial shampoos are alternative adjunctive treatments for tinea capitis arising from M. canis. In addition, contact with the shampoos for at least 5 minutes appears to be optimal.

References

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Published

2020-12-08

How to Cite

Bunyaratavej, S., Kiratiwongwan, R., Suphatsathienkul, P., Munprom, K., Matthapan, L., Supcharoenkul, S., Lertrujiwanit, K., Prasong, W., & Leeyaphan, C. (2020). Effect of Different Shampoos and Contact Time on Microsporum canis Infected Hair: In vitro Model Study. Thai Journal of Dermatology, 36(4), 149–156. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/244580

Issue

Vol. 36 No. 4 (2020): October - December

Section

Original articles

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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น