Case Report of Cutaneous Rosai-Dorfman Disease with Bilateral Anterior Uveitis

Authors

  • Thanet Pongcharoensuk DIVISION OF DERMATOLOGY, DEPARTMENT OF MEDICINE, PHRAMONGKUTKLAO HOSPITAL, BANGKOK, THAILAND.
  • Chutika Srisuttiyakorn DIVISION OF DERMATOLOGY, DEPARTMENT OF MEDICINE, PHRAMONGKUTKLAO HOSPITAL, BANGKOK, THAILAND.

Keywords:

Rosai-Dorfman disease, sinus histiocytosis with massive lymphadenopathy, uveitis, non-langerhan cell histiocytosis

Abstract

Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare, idiopathic, benign lympho-histiocytic proliferative disorder, which was first described by Rosai and Dorfman in 1969. It most commonly affects young people with predominance in the male population. Rosai-Dorfman disease was initially described with bilateral painless lymphadenopathy, fever, leukocytosis, and polyclonal gammopathy. Extranodal involvement has been reported in 25-40% of cases, the most common involving the skin, respiratory tract, soft tissue, visceral organs and central nervous system3. Ocular involvement is relatively rare, and mostly characterized as lymphoproliferation in the soft tissues of the orbit and the eyelids2. Cutaneous Rosai-Dorfman disease is present in about 3/100 case of Rosai-Dorfman disease with age distribution range from 15-68 years and clinically characterized by red-brown-yellow localized or disseminated papules, plaques, or nodules at any location4. Here we report an interesting case of extranodal Rosai-Dorfman disease with cutaneous lesions and ophthalmic manifestations of bilateral anterior uveitis.

References

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Published

2021-06-09

How to Cite

Pongcharoensuk, T., & Srisuttiyakorn, C. (2021). Case Report of Cutaneous Rosai-Dorfman Disease with Bilateral Anterior Uveitis. Thai Journal of Dermatology, 37(2), 63–8. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/247633

Issue

Vol. 37 No. 2 (2021): April - June

Section

Case Report

License

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