Glomuvenous Malformations: A Case Report and Review

Abstract

Glomuvenous malformations (GVMs), previously known as glomangiomas, are benign localized tumors of the skin arising from glomus cells. GVMs often appear during infancy and childhood as a small solitary, or multiple papulonodular lesions commonly located on extremities. The disease diagnosis is based on clinical and microscopic finding with a definite diagnosis confirmed by genetic test. The treatment of choice is surgical resection for isolated GVMs. Sclerotherapy and vascular laser therapy may also be helpful for multiple variant. In this report, we describe a rare case of sporadic GVMs in a 22-year-old male presented with a history of multiple dark violaceous to bluish papules and nodules on the left wrist, left ankle and left side of lower back since he was 10 years old. His clinical and histopathological features were compatible with disseminated pattern of multiple GVMs. In addition, literature review on the clinical features, diagnosis, differential diagnosis, clinical course and treatment of the disease was done.