Oral Hairy Leukoplakia in pemphigus Patients: A Case Series

Authors

  • Praphathip Rattanathipa INSTITUTE OF DERMATOLOGY, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Tanaporn Borriboon INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Chavalit Supsrisunjai INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Pinnaree Kattipathananpong INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.

Keywords:

Oral hairy leukoplakia, Epstein-Barr virus, pemphigus

Abstract

Oral hairy leukoplakia (OHL) is an Epstein-Barr virus (EBV)-associated lesion of the oral mucosa and most commonly seen in human immunodeficiency virus (HIV)-positive patients. However, OHL has also been reported in HIV-negative immunosuppressed patients. We present two cases of OHL in pemphigus patients. One lesion was located on the lateral borders of tongue and the other was located on the dorsal of tongue. The diagnosis was confirmed by clinical, polymerase chain reaction for EBV from lesion scraping and excluded oral candidiasis. Smoking, advanced aged and oral pemphigus may be the contributing factors to develop OHL in these patients. Oral acyclovir and gentian violet are effective treatments for OHL in our patients.

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Published

2022-06-08

How to Cite

Rattanathipa, P., Borriboon, T., Supsrisunjai, C., & Kattipathananpong, P. (2022). Oral Hairy Leukoplakia in pemphigus Patients: A Case Series. Thai Journal of Dermatology, 38(2), 54–60. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/255872