A Man with Chronic Painful Penile Ulcer

Abstract

Penile calciphylaxis or calcific uremic arteriolopathy of the penile arteries is a rare condition of calcium deposition in the arteries associated with poor prognosis and high mortality rate. This phenomenon usually coexisted with hemodialysis dependent end stage renal disease status. The sign and symptom are intolerable pain, associated with discoloration of the skin and infection. More than half of genital calciphylaxis patients will be diagnosed along with concurrent extra-genital calciphylaxis. It is crucial to diagnose the patient early due to its high morbidity and mortality nature. Currently, the definite treatment in inconclusive, eradication of risk factors and correction of imbalanced electrolyte are recommended. There are reports of successful treatment with sodium thiosulfate, phosphodiesterase-5 inhibitors.