Sebaceous Gland Hyperplasia: An Atypical Presentation of Birt-Hogg-Dubé Syndrome

Authors

  • Rujira Leetanapon DERMATOLOGY UNIT, DIVISION OF INTERNAL MEDICINE, PHRAMONGKUTKLAO HOSPITAL, BANGKOK, THAILAND.
  • Supapat Laodheerasiri DERMATOLOGY UNIT, DIVISION OF INTERNAL MEDICINE, PHRAMONGKUTKLAO HOSPITAL, BANGKOK, THAILAND.

Keywords:

Birt-Hogg-Dubé syndrome, multiple sebaceous gland hyperplasia, folliculin gene

Abstract

Birt-Hogg-Dubé syndrome (BHD) is an inherited autosomal dominant hamartoma disorder, characterized by benign tumors of the hair follicle, lung cysts, and renal neoplasia. It is caused by germ-line mutations in the folliculin (FLCN) gene. Cutaneous manifestations are mainly presented with folliculoma or trichodiscoma. We report a case of a BHD patient with sebaceous gland hyperplasia on the face without other skin lesions. The diagnosis is confirmed by clinical symptoms and folliculin gene mutation. Ablative carbon dioxide laser is the effective treatment for sebaceous gland hyperplasia in our patient.

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References

References

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Published

2022-09-07

How to Cite

Leetanapon, R., & Laodheerasiri, S. (2022). Sebaceous Gland Hyperplasia: An Atypical Presentation of Birt-Hogg-Dubé Syndrome. Thai Journal of Dermatology, 38(3), 114–119. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/258406