A Case Report of Unrecognized Lepromatous Leprosy Occurring in Conjunction with Pemphigus Vulgaris
Keywords:
Lepromatous leprosy, Pemphigus vulgaris, Oral immunosuppressive agentsAbstract
Leprosy is a chronic, infectious disease of a significant public health concern, primarily affecting the skin and peripheral nerves. The causative agent of this disease is Mycobacterium leprae, and despite its recognition as an ancient affliction, it continues to be occasionally encountered in the southern regions of Thailand. The manifestation and progression of leprosy are known to be influenced by the host's genetic background and immune response. We present a case of a 45-year-old Thai male who developed new infiltrative papules and nodules while undergoing oral immunosuppressive therapy for the treatment of his underlying pemphigus vulgaris condition. Upon histopathological examination, the presence of histiocytes containing abundant acid-fast bacilli was observed. The patient was successfully treated through a 2-year course of multidrug therapy. This case highlights the challenges in diagnosing leprosy in immunocompromised individuals and underscores the importance of vigilant recognition of the disease by healthcare practitioners. It is imperative that medical professionals remain aware of the potential for leprosy to present in unexpected ways and take necessary steps to diagnose and treat the disease effectively.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น