A case report of Degos disease in patient presented with jejunal perforation and peritonitis

Authors

  • Sujirod Hanthavichai DIVISION OF DERMATOLOGY, DEPARMENT OF MEDICINE, FACULTY OF MEDICINE, CHULALONGKORN UNIVERSITY, BANGKOK, THAILAND
  • Ratchathorn Panchaprateep DIVISION OF DERMATOLOGY, DEPARMENT OF MEDICINE, FACULTY OF MEDICINE, CHULALONGKORN UNIVERSITY, BANGKOK, THAILAND
  • Noppadon Noppakun DIVISION OF DERMATOLOGY, DEPARMENT OF MEDICINE, FACULTY OF MEDICINE, CHULALONGKORN UNIVERSITY, BANGKOK, THAILAND

Keywords:

Degos disease, intestinal perforation

Abstract

Degos disease or malignant atrophic papulosis is a progressive small- and medium-size arterial occluding disease, leading to tissue infarction in many organs such as the skin, gastrointestinal and nervous systems. This study reported a 56-year-old female patient who presented with abdominal pain due to jejunal perforation with peritonitis. Later, she developed generalized multiple central white scar and telangiectatic rim on trunk, extremities, palm and sole. The histopathology is characteristic, with wedge-shaped area of homogenized collagen fibers and lymphocytic vasculitis in the dermis. Unfortunately, she died from sepsis and multiorgan failure.

References

Scheinfeld N. Pairing and comparing nine diseases with Degos Disease (Malignant Atrophic Papulosis): an attempt to illustrate our understanding and direct future inquiry. Dermatol Online J 2009; 15: 10.

Notash AY, Mazoochy H, Mirshams M, Nikoo A. Lethal systemic Degos disease with prominent cardio-pulmonary involvement. Saudi Med J 2008; 29: 133-7.

Tan WP, Chio MT, Ng SK. Generalized red papules with gastrointestinal complications. Diagnosis: malignant atrophic papulosis (Degos' disease). Clin Exp Dermatol 2007; 32: 615-6.

Lankisch MR, Johst P, Scolapio JS, Fleming CR. Acute abdominal pain as a leading symptom for Degos' disease (malignant atrophic papulosis). Am J Gastroenterol 1999; 94: 1098-9

Asherson RA, Cervera R. Antiphospholipid syndrome. J Invest Dermatol 1993; 100: 21S-27S.

Saglik E, Baykal C, Buyukbabani N, Inanc M. Malignant atrophic papulosis: endocardial involvement and positive anticardiolipin antibodies. J EurAcadDermatolVenereol 2006; 20: 602-3.

Ortiz A, Ceccato F, Albertengo A, Roverano S, Iribas J, Paira S. Degos cutaneous disease with features of connective tissue disease. J Clin Rheumatol 2010;16:132-4.

Scheinfeld N. Malignant atrophic papulosis.Clin Exp Dermatol 2007;32:483-7

Zhu KJ, Zhou Q, Lin AH, Lu ZM, Cheng H. The use of intravenous immunoglobulin in cutaneous and recurrent perforating intestinal Degos disease (malignant atrophic papulosis). Br J Dermatol 2007;157:206-7.

Magro C, Shapiro L, Johnson B, Salmon J, Whelan P. Rheumatology Grand Rounds Hospital for Special Surgery (New York City) Degos Disease. Feb 10, 2010. In press.

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Published

2026-06-11

How to Cite

Hanthavichai, S., Panchaprateep, R., & Noppakun, N. (2026). A case report of Degos disease in patient presented with jejunal perforation and peritonitis. Thai Journal of Dermatology, 27(3), 198–203. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/282955

Issue

Vol. 27 No. 3 (2011): July-September

Section

Case Report

License

Copyright (c) 2011 Thai Journal of Dermatology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น