Dyschromatosis universalis hereditaria with face and acral predomination : a case report and literature review
Keywords:
dyschromatosis universalis hereditaria(DUH), dyschromatosisAbstract
Dyschromatosis universalis hereditaria (DUH) is a rare dermatologic disorder with autosomal dominant inheritance. DUH characterized by generalized, asymptomatic, dyspigmented macules of varying sizes and shapes. Facial, palm, soles and mucosal involvements are uncommon. However, those area have been described in several reports of DUH. The pathogenesis of DUH is not known but was proposed that DUH is a disorder of abnormal melanosome synthesis rate. We report a 23-year old Thai male with generalized spotty hypopigmented and hyperpigmented macules located predominantly at face and acral area. His first degree relatives had similar dyspigmentation. This presence of truncal involvement and histopathological findings are compatible the diagnosis of with dyschromatosis universalis hereditaria. This patent is a case of DUH with atypical distributions of lesions.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
