Efficacy of Fractional Laser Photothermolysis in the Treatment of Atrophic Acne Scar in Thai Patients, Comparison between 25 mJ, 250 MTZS/cm2 and 25 mJ, 500 MTZS/cm2 : A Randomized Single-blind Split Face Study

Authors

  • Jade Wititsuwannakul DIVISION OF DERMATOLOGY, DEPARTMENT OF MEDICINE, FACULTY OF MEDICINE, CHULALONGKORN UNIVERSITY, BANGKOK, THAILAND
  • Nopadon Noppakun DIVISION OF DERMATOLOGY, DEPARTMENT OF MEDICINE, FACULTY OF MEDICINE, CHULALONGKORN UNIVERSITY, BANGKOK, THAILAND

Keywords:

Fractional laser photothermolysis, Acne scar

Abstract

Background: Fractional photothermolysis represents a  method of  treatment for acne scars without significant side effects.

Objective: To evaluate the effectiveness and side effects of the fractional laser in the treatment of atrophic acne scar and compare the results  between  different  treatment density.

Material and Methods: 46 patients were enrolled in this trial. Each patient was randomized to receive treatment on half of the face with fractional photothermolysis  25 mJ, 250 MTZs/cm2, while the other half was treated with 25 mJ, 500 MTZs/cm2.The treatments were done with 1,550 nm Erbium fiber fractional laser every 4 weeks for 5 sessions. Clinical assessments and side effects graded by dermatologists were also obtained pretreatment and at 4,12 and 24 weeks after the last treatment.

Result: Modest improvement in acne scars was observed in majority of patients on both sides with minimal side effects.

Conclusion: The fractional photothermolysis is an effective treatment for atrophic acne scar.

References

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Published

2026-06-11

How to Cite

Wititsuwannakul, J., & Noppakun, N. (2026). Efficacy of Fractional Laser Photothermolysis in the Treatment of Atrophic Acne Scar in Thai Patients, Comparison between 25 mJ, 250 MTZS/cm2 and 25 mJ, 500 MTZS/cm2 : A Randomized Single-blind Split Face Study. Thai Journal of Dermatology, 27(2), 91–102. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/282962

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