Factors related to unpleasant symptoms among postoperative brain tumor persons

Main Article Content

Boonsita Thingakrue
Noppamat Pudtong

Abstract

 


This study aimed to examine unpleasant symptoms and the factors associated with such symptoms among individuals with brain tumors following surgical intervention. The investigated variables included gender, age, tumor location, comorbidities, physical activity, nutritional status, resilience, and social support. Participants of 120 individuals were recruited through purposive sampling based on predefined inclusion criteria. Research instruments included a personal data form, illness record form, Unpleasant Symptom Assessment Scale, Charlson Comorbidity Index (CCI), International Physical Activity Questionnaire–Short Form (IPAQ-SF), Mini Nutritional Assessment (MNA), Resilience Quotient (RQ-20), and the Social Support Questionnaire (SSQ Part 2). The content validity of all instruments was evaluated by five experts, and reliability coefficients ranged from 0.86 to 0.99. Data analysis was performed using descriptive statistics, Pearson’s correlation, and Eta. The results indicated that the mean overall severity score of unpleasant postoperative symptoms was 2.54 (SD = 1.47), reflecting a mild level of symptom severity. The most commonly reported symptoms were headache, insomnia, and fatigue, respectively. Significant correlations were found between unpleasant symptoms and comorbidities (r = 0.467), nutritional status (r = –0.444), resilience (r = –0.355), and physical activity (r = –0.242), all at the .05 level of significance. However, gender, age, tumor location, and social support were not significantly associated with unpleasant symptoms following brain tumor surgery.


         

Article Details

How to Cite
Thingakrue, B., & Pudtong, N. . (2026). Factors related to unpleasant symptoms among postoperative brain tumor persons. Thai Journal of Nursing, 75(1), 1–10. retrieved from https://he02.tci-thaijo.org/index.php/TJN/article/view/275440
Section
Research Article

References

กระทรวงสาธารณสุข กรมสุขภาพจิต. (2567). แบบประเมินความเข้มแข็งทางใจ. https://mhc5.dmh.go.th/appcenter/rq/index.php

พรพิมล รัตนาวิวัฒน์พงศ์, อารมณ์ ขุนภาษี, ฉกาจ ผ่องอักษร, และภัทราวุธ อินทรกำแหง. (2549). ความเที่ยงตรงและความน่าเชื่อถือของแบบสอบถามสากลเรื่องกิจกรรมทางกายชุดสั้น ฉบับ ภาษาไทย. เวชศาสตร์ฟื้นฟูสาร, 16(3), 147-160.

ภัทรา พิมสาร และชนกพร จิตปัญญา. (2559). ความสัมพันธ์ระหว่างกลุ่มอาการไม่สุขสบาย วิธีการเผชิญความ เครียดและคุณภาพชีวิตด้านสุขภาพของผู้ป่วยโรคเนื้องอกสมองหลังผ่าตัด. วารสารมหาวิทยาลัยหัวเฉียววิชาการ, 20(39), 57-68.

ภิญาภร โตญาติมาก, เกศรินทร์ อุทริยะประสิทธิ์, วัลย์ลดา ฉันท์เรืองวณิชย์, บรรพต สิทธินามสุวรรณ, และสุชาดา ภัทรมงคลฤทธิ์ (2562). ปัจจัยทำนายความบกพร่องด้านการรู้คิดในผู้ป่วยภายหลังการผ่าตัดเนื้องอกสมอง. วารสารสภาการพยาบาล, 34(4), 64-79.

อำนวยพร อาษานอก. (2549). ปัจจัยคัดสรรที่มีความสัมพันธ์กับคุณภาพชีวิตของผู้ป่วยวัยผู้ใหญ่โรคเนื้องอกสมอง [วิทยานิพนธ์ปริญญามหาบัณฑิต ไม่ได้ตีพิมพ์], จุฬาลงกรณ์มหาวิทยาลัย.

Bates, A., Gonzalez-Viana, E., Cruickshank, G., Roques, T. , & Guideline Committee (2018). Primary and metastatic brain tumours in adults: Summary of NICE guidance. BMJ (Clinical research ed.), 362, Article k2924. https://doi.org/10.1136/bmj.k2924

Bowyer, A. J., & Royse, C. F. (2016). Postoperative recovery and outcomes-What are we measuring and for whom. Anaesthesia, 71(Suppl. 1), 72–77. https://doi.org/10.1111/anae.13312

Cederholm, T., Volkert, D., Beck, A. M., Cruz-Jentoft, A., Goisser, S., Hooper, L., Kiesswetter, E., Maggio, M., Raynaud-Simon, A., Sieber, C. C., Sobotka, L., van Asselt, D., Wirth, R., & Bischoff, S. C. (2019). ESPEN guideline on clinical nutrition and hydration in geriatrics. Clinical Nutrition, 38(1), 10–47. https://doi.org/10.1016/j.clnu.2018.05.024

Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Diseases, 40(5), 373–383. https://doi.org/10.1016/0021-9681(87)90171-8

Choi, H. R., Song, I. A., Park, H. Y., & Oh, T. K. (2023). Association between insomnia disorder and mortality among patients who underwent craniotomy for brain tumor resection: A South Korean nationwide cohort study. Sleep Breath, 27(1), 329-336. https://doi.org/10.1007/s11325-022-02586-2

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008). From inflammation to sickness and depression: When the immune system subjugates the brain. Nature Reviews Neuroscience, 9(1), 46–56. https://doi.org/10.1038/nrn2297

Duffau, H. (2014). The huge plastic potential of adult brain and the role of connectomics: New insights provided by serial mappings in glioma surgery. Cortex, 58, 325-337. https://doi.org/10.1016/j.cortex.2013.08.005

Guigoz, Y., Vellas, B., & Garry, P. J. (1994). Mini nutritional assessment: A practical assessment tool for grading the nutritional state of elderly patients. Facts Research of Gerontology, 4(2), S15-S59.

Hannegan, L. (1989). Transient cognitive changes after craniotomy. Journal of Neuroscience Nursing, 21(3), 165–170. https://doi.org/10.1097/01376517-198906000-00005

Hanucharurnkul, S. (1988). Social support, self-care, and quality of life in cancer patients receiving radiotherapy in Thailand [Unpublished doctoral dissertation]. Wayne State University.

Ilgen, M., Zivin, K., McCammon, R. J., & Valenstein, M. (2008). Pain and suicidal thoughts, plans and attempts in the United States. General Hospital Psychiatry, 30(6), 521-527. https://doi.org/10.1016/j.genhosppsych.2008.09.003

Knezevic, E., Nenic, K., Milanovic, V., & Knezevic, N. N. (2023). The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells, 12(23), Article 2726. https://doi.org/10.3390/cells12232726

Koelwyn, G. J., Quail, D. F., Zhang, X., White, R. M., & Jones, L. W. (2017). Exercise-dependent regulation of the tumour microenvironment. Nature Reviews Cancer, 17(10), 620-632. https://doi.org/10.1038/nrc.2017.78

Lenz, E. R., Pugh, L. C., Milligan, R. A., Gift, A., & Suppe, F. (1997). The middle-range theory of unpleasant symptoms: An update. Advances in Nursing Science, 19(3), 14-27. https://doi.org/10.1097/00012272-199703000-00003

Miklja, Z., Gabel, N., Altshuler, D., Wang, L., Hervey-Jumper, S. L., & Smith, S. (2022). Exercise improves health-related quality of life, sleep, and fatigue domains in adult high- and low-grade glioma patients. Supportive Care in Cancer, 30(2), 1493-1500. https://doi.org/10.1007/s00520-021-06566-2

Reponen, E., Tuominen, H., Hernesniemi, J., & Korja, M. (2015). Postoperative complications and functional outcome after surgery for brain tumors. Acta Neurochirurgica, 157(10), 1765–1773.

Schaefer, C., Coyne, J. C., & Lazarus, R. S. (1981). The health-related functions of social support. Journal of Behavioral Medicine, 4(4), 381–406. https://doi.org/10.1007/BF00846149

Schei, S., Sagberg, L. M., Bø, L. E., Reinertsen, I., & Solheim, O. (2023). Association between patient- reported cognitive function and location of glioblastoma. Neurosurgical Review, 46(1), 282. https://doi.org/10.1007/s10143-023-02177-z

Steinruecke, M., Pronin, S., Gherman, A. V., Emelifeonwu, J., & Liaquat, I. (2023). Survival and complications following supra and infratentorial brain metastasis resection. The Surgeon, 21(5), Article e279–e286. https://doi.org/10.1016/j.surge.2023.01.006

Utriyaprasit, K. (2001). The relationship between recovery symptoms and functional outcomes in Thai CABG patients [Unpublished doctoral dissertation]. Case Western Reserve University.

Valko, P. O., Siddique, A., Linsenmeier, C., Zaugg, K., Held, U., & Hofer, S. (2015). Prevalence and predictors of fatigue in glioblastoma: A prospective study. Neuro- oncology, 17(2), 274-281. https://doi.org/10.1093/neuonc/nou127

Zhang, X., Li, Y., Zhang, D., Zhong, Y., & Li, T. (2023). Fatigue and its contributing factors in Chinese patients with primary pituitary adenomas. Journal of Oncology, 2023, Article 9876422. https://doi.org/10.1155/2023/9876422

Zhao, Y., Hu, B., Liu, Q., Wang, Y., Zhao, Y., & Zhu, X. (2022). Social support and sleep quality in patients with stroke: The mediating roles of depression and anxiety symptoms. International Journal of Nursing Practice, 28(3), Article e12939. https://doi.org/10.1111/ijn.12939