The application of platelet rich fibrin in dentistry
Keywords:
Platelet rich fibrin (PRF), Wound healing, DentistryAbstract
Platelet rich fibrin (PRF) is an autgenous biomaterial. PRF which was developed from platelet rich plasma (PRP), is considered as a second generation of the platelet concentrate and mainly used to promote the cell proliferation. PRF is consists of platelet and leukocyte attached to a fibrin matrix. It can serve as a resorbable membrane which entrapped and released the growth factors and cytokines to accelerate the wound healing process in both hard and soft tissue. In recent times, it has been used various disciplines in dentistry, for example, oral and maxillofacial surgery, periodontology and endodontology, which mainly applies to stimulate the wound healing of the oral lesion and improves the prognosis of diseases.
References
Agrawal, M., & Agrawal, V. (2014). Platelet Rich Fibrin and its Applications in Dentistry- A Review Article. National Journal of Medical and Dental Research, 2(3), 51-58.
Anilkumar, K., Geetha, A., Umasudhakar, Ramakrishnan, T., Vijayalakshmi, R., & Pameela, E. (2009). Platelet-rich-fibrin: A novel root coverage approach. J Indian Soc Periodontol, 13(1), 50-54.
Chang, Y. C., & Zhao, J. H. (2011). Effects of platelet-rich fibrin on human periodontal ligament fibroblasts and application for periodontal infrabony defects. Aust Dent J, 56(4), 365-371.
Choukroun, J., Diss, A., Simonpieri, A., Girard, M. O., Schoeffler, C., Dohan, S. L., et al. (2006a). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101(3), e56-60.
Choukroun, J., Diss, A., Simonpieri, A., Girard, M. O., Schoeffler, C., Dohan, S. L., et al. (2006b). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101(3), 299-303.
Corso, M. D., Toffler, M., & Ehrenfest, D. M. D. (2012). Use of an autologous leukocyte and Platelet-Rich Fibin (L-PRF) Membrane in Post-Avulsion Sites: An Overview of Choukroun's PRF. The Journal of Implant&Advance Clinical Dentistry, 1(9).
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J., Mouhyi, J., et al. (2006a). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101(3), e37-44.
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J., Mouhyi, J., et al. (2006b). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101(3), e45-50.
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J., Mouhyi, J., et al. (2006c). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101(3), e51-55.
Dvorak, H. F., Harvey, V. S., Estrella, P., Brown, L. F., McDonagh, J., & Dvorak, A. M. (1987). Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing. Lab Invest, 57(6), 673-686.
Gassling, V., Douglas, T., Warnke, P. H., Acil, Y., Wiltfang, J., & Becker, S. T. (2010). Platelet-rich fibrin membranes as scaffolds for periosteal tissue engineering. Clin Oral Implants Res, 21(5), 543-549.
Hoaglin, D. R., & Lines, G. K. (2013). Prevention of localized osteitis in mandibular third-molar sites using platelet-rich fibrin. Int J Dent, 2013, 875380.
Jain, V., Triveni, M. G., Kumar, A. B., & Mehta, D. S. (2012). Role of platelet-rich-fibrin in enhancing palatal wound healing after free graft. Contemp Clin Dent, 3(Suppl 2), S240-243.
Karunakar, P., Prasanna, J. S., Jayadev, M., & Shravani, G. S. (2014). Platelet-rich fibrin, “a faster healing aid” in the treatment of combined lesions: A report of two cases. J Indian Soc Periodontol, 18(5), 651-655.
Kawamura M., & Urist MR. (1988). Human fibrin is a physiologic delivery system for bone morphogenetic protein. Clin Orthop Relat Res, 235, 320-310.
Khetarpal, A., Chaudhry, S., Talwar, S., & Verma, M. (2013). Endodontic management of open apex using MTA and platelet – rich fibrin membrane barrier: A newer matrix concept. J Clin Exp Dent, 5(5), 291-294.
Khiste, S. V., & Tari, R. N. (2013). Platelet-Rich Fibrin as a Biofuel for Tissue Regeneration. Hindawi Publishing Corparation.
Kumar, A. P., Fernandes, B., & Surya, C. (2011). Platelet rich fibrin: A promising approach for root coverage. Journal of Interdicliplinary Dentistry, 1(2), 115-118.
Li, Q., Pan, S., Dangaria, S. J., Gopinathan, G., Kolokythas, A., Chu, S., et al. (2013). Platelet-rich fibrin promotes periodontal regeneration and enhances alveolar bone augmentation. Biomed Res Int, 2013, 638043.
Loike, J. D., Sodeik, B., Cao, L., Leucona, S., Weitz, J. I., Detmers, P. A., et al. (1991). CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen. Proc Natl Acad Sci U S A, 88(3), 1044-1048.
Margolis DJ, Kantor J, Santanna J, Strom BL, & Berlin JA. (2001). Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers. Diabetes Care, 24(3), 483-488.
Mishra, N., Narang, I., & Mittal, N. (2013). Platelet-rich fibrin-mediated revitalization of immature necrotic tooth. Contemp Clin Dent, 4(3), 412-415.
Ross R., Glomset J., Kariya B., & Harker L. (1974). A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci U S A, 71(4), 1207-1210.
Rozman P, & Bolta Z. (2007). Use of platelet growth factors in treating wounds and soft-tissue injuries. Acta Dermatovenerol Alp Panonica Adriat, 16, 156-165.
Shivashankar, V. Y., Johns, D. A., Vidyanath, S., & Sam, G. (2013). Combination of platelet rich fibrin, hydroxyapatite and PRF membrane in the management of large inflammatory periapical lesion. J Conserv Dent, 16(3), 261-264.
Whitman, D. H., Berry, R. L., & Green, D. M. (1997). Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg, 55(11), 1294-1299.
Yadav P, Pruthi PJ, Naval RR, Talwar S, & Verma M. (2015). Novel use of platelet-rich fibrin matrix and MTA as an apical barrier in the management of a failed revascularization case. Dent Traumatol, 31(4), 328-331.
Yelamali, T., & Saikrishna, D. (2015). Role of platelet rich fibrin and platelet rich plasma in wound healing of extracted third molar sockets: a comparative study. J Maxillofac Oral Surg, 14(2), 410-416.
