A Comparative Study of Pain Reduction during Scaling between Lidocaine Hydrochloride, Benzydamine Hydrochloride Mouthrinses and Benzocaine with Tetracaine Hydrochloride Topical Gel

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รุ่งนภา ทรัพย์สุพรรณ
วรรณา โล้วพฤกษ์มณี
ภัทรา ชุนพงษ์ทอง
ดุจฤดี เลิศเพียรธรรม

Abstract

Pain generated by scaling and rooting was commonly compliant by almost all of the patients in a variable degree. The purpose of this study was to evaluate and compare the efficacy of lidocaine hydrochloride (Xylocaine viscous), benzydamine hydrochloride (Difflam) mouthrinses and benzocaine/tetracaine hydrochloride topical gel (ZAP) in pain reduction during scaling. In a single center, randomized, split-mouth design and controlled clinical trial was carried out on 60 patients. In each patient, one maxillary dental quadrant was randomly received Xylocaine viscous (n = 20) or Difflam (n = 20) or ZAP (n = 20), contralateral was control, recorded pain on a 100 millimeter visual analog scale (VAS). T- test revealed that the difference between mean VAS values of intervention and control quadrants was significant in Xylocaine viscous group (p = 0.017) and ZAP group (p <0.001), but not in Difflam group (p = 0.126). Comparing pain reduction in terms of a ratio, analyzed by ANOVA and Bonferroni, mean percentage in Xylocaine viscous group (62.4) and ZAP group (69.1) were significantly higher than Difflam group (23.2) (p <0.001). Pleasantness, patient preferred to use mouthrinses 80 percent, topical gel 90 percent.

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1.
ทรัพย์สุพรรณ ร, โล้วพฤกษ์มณี ว, ชุนพงษ์ทอง ภ, เลิศเพียรธรรม ด. A Comparative Study of Pain Reduction during Scaling between Lidocaine Hydrochloride, Benzydamine Hydrochloride Mouthrinses and Benzocaine with Tetracaine Hydrochloride Topical Gel. Th Dent PH J [Internet]. 2011 Dec. 31 [cited 2024 Dec. 27];16(2):43-54. Available from: https://he02.tci-thaijo.org/index.php/ThDPHJo/article/view/178319
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References

1. Watts T.L.P. Periodontics in practice, Science with humanity. New York : Martin Dunitz, 2000, p 143-155.

2. ณรงค์ศักดิ์ เหล่าสีสิทธิ์, Perio Tips with Ultrasonic Equipment. Butterfly, Acteon (Thailand) 2550; 7: 12-15.

3. Weinberg M.A., Westphal C., Froum S.J. and Palat M., Comprehensive1747periodontics for the dental hygienist. 2nd ed., New Jersey : Pearson Prentice Hall, 2006, p 592.

4. Canakci V. and Canakci C.F. Pain levels in patients during periodontal probing and mechanical non-surgical therapy. Clin. Oral Investig. 2007; 11(4): 377-383.

5. Paarmann C. and Royer R. Pain control for dental practitioners. An interactive approach. Philadelphia : Lippincott Williams & Wilkins, 2008, p 1.

6. MagnusSon I., Jeffcoat M.K., Donaldson D., Otterbom I.L. and Henriksson J. Quantification and analysis of pain in nonsurgical scaling and/or root planing. JADA. 2004; 135(12): 1747-1754.

7. Kumar P.S. and Leblebicioglu B. Pain control during nonsurgical periodontal therapy. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995).” Compend. Contin. Educ. Dent. 2007; 28(12): 666-669.

8. Magnusson I., Geurs N.C., Harris P.A., Hefti A.F., Mariotti A.J., Mauriello S.M. et al. Intrapocket anesthesia for scaling and root planing in pain-sensitive patients. J. Periodontol. 2003; 74(5): 597-602.

9. Jeffcoat M.K., Geurs N.C., Magnusson I., MacNeill S.R., Mickels N., Roberts F. et al. Intrapocket anesthesia for scaling and root planing: results of a doubleblind multicenter trial using lidocaine prilocaine dental gel. J. Periodontol. 2001; 72(7): 895-900.

10. Svensson P., Petersen J.K. and Svensson H. Efficacy of a topical anesthetic on pain and unpleasantness during scaling of gingival pockets. Anesth. Prog. 1994; 41(2): 35-39.

11. Carr M.P. and Horton J.E. Evaluation of a transor al delivery system for topical anesthesia. JADA 2001; 132(12): 1714-1719.

12. Pandit N., Gupta R., Chandoke U. and Gugnani S. Comparative evaluation of topical and electronic anesthesia during scaling and root planing. J. Periodontol. 2010; 81(7):1035-1040.

13. Stoltenberg J.L., Osborn J.B., Carlson J.F., Hodges J.S. and Michalowicz B.S. A preliminary study of intra-pocket topical versus injected anaesthetic for scaling and root planing. J. Clin. Periodontol.2007; 34(10): 892-896.

14. Carr M.P. and Horton J.E. Clinical evaluation and comparison of 2 topical anesthetics for pain caused by needle sticks and scaling and root planing. J. Periodontol. 2001; 72(4):479-484.

15. Meechan J.G. Effective topical anesthetic agents and techniques. Dent. Clin. North Am. 2002; 46(4):759-766.

16. Friskopp J., Nilsson M. and Isacsson G. The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing. J. Clin. Periodontol. 2001; 28(5):453-458.

17. AstraZeneca Canada Inc. Xylocaine® viscous 2% (lidocaine hydrochloride solution). Ontario: AstraZeneca Canada Inc; 2009.

18. TIMS (Thailand). Anesthetics. 99. Bangkok: United Business Media; 2005.

19. American Society of Health-System Pharmacists Inc. Lidocaine Hydrochloride (Local Anesthetic). Bethesda: American Society of Health-System Pharmacists Inc; 2008.

20. Froom J. and Boisseau V. Benzydamine oral rinse for sore throat. Current Therapeutic Research 1979;26(6): 856-861.

21. ชนวัธน์ เทศะวิบูล. การใช้ Benzydamine HCl เพื่อป้องกันการเกิด Radiation Mucositis. Medical Progress CME 2004: 1-4.

22. Epstein J.B., Silverman S., Paggiarino D.A., Crockett S., Schubert M.M., Senzer N.N. et al. Benzydamine HCl for prophylaxis of radiation induced oral mucositis. Cancer 2001; 92(4): 875-885.

23. InovaPharm. Difflam. [cited 2010 November 24]. Available from: URL:http://www.inovapharma.com/ our-products/product-detail/Difflamsolution/413/

24. Germiphene. ZAP. [cited 2010 November 24]. Available from: URL: http://www.germiphene.com/ newweb/products/ZAP_topical_gel/ product%20profile. pdf.