Clinical Features and Pathological Analysis of Lacrimal Gland Tumors in 38 Patients

Authors

  • Duangmontree Rojdamrongratana Department of Ophthalmology, Faculty of Medicine, thammasat university
  • Suwit Kongbundansuk Department of Ophthalmology, Faculty of Medicine, Thammasat university
  • Waraporn Mitsuntisuk Department of Ophthalmology, Faculty of Medicine, Thammasat university
  • Pawarit Wanichsetakul Department of Ophthalmology, Faculty of Medicine, Thammasat university
  • Gaanchisa Vongchaiyakit Department of Ophthalmology, Faculty of Medicine, Thammasat university

Keywords:

lacrimal gland tumor, lymphoma

Abstract

Objective: We reviewed the clinical features and pathological findings of lacrimal gland tumors in 38 patients.

Methods: This is a retrospective case series study. Clinical data of 38 patients with lacrimal gland tumors who
received treatment in Thammasat Hospital Thailand from January 2017 to December 2020 were retrospectively analyzed
including age, gender, clinical presentation, imaging examination data and pathological findings.

Results: Among 38 cases, 12 patients (31.58%) were male and 26 (68.42%) were female. The age distribution
ranged from 11 years to 78 years of age, with an average age of 53 years. All of the benign tumors added up to 23
cases (60.53%), pleomorphic adenoma 2 cases (5.26%), IgG4-related disease 3 cases, (7.89%), amyloidosis 1 cases
(2.63%), sarcoidosis 1 cases (2.63%), lymphoid hyperplasia 4 cases (10.52%) and non-specific dacryoadenitis 11 cases
(28.95%) were the most common cases in the benign lacrimal gland occupying tumors. There were 15 cases (39.47%)
of malignant tumors; adenocarcinoma 1 cases (2.63%), acute myeloid leukemia 1 cases (2.63%) and lymphoma 13
cases (34.21%). Lymphoma had the highest incidence among the malignant lacrimal gland occupying tumors. The most
common reasons for seeking medical treatment were eyelid mass 37 cases (97.37%), proptosis 15 cases (39.47%) and
periorbital pain 4 cases (10.53%).

Conclusions: Most lacrimal gland tumors remains benign. Non-specific dacryoadenitis is known to be the leading
cause of such tumor, where the most often manifests as eyelid mass. Likewise, malignant lacrimal gland tumor clinically
appears as eyelid mass, and is commonly caused by lymphoma.

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Published

2021-12-27

Issue

Vol. 35 No. 2 (2021): July-December

Section

Original Articles

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The Thai Journal of Ophthalmology (TJO) is a peer-reviewed, scientific journal published biannually for the Royal College of Ophthalmologists of Thailand. The objectives of the journal is to provide up to date scientific knowledge in the field of ophthalmology, provide ophthalmologists with continuing education, promote cooperation, and sharing of opinion among readers.

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