Simultaneous Bilateral Central Retinal Vein Occlusion as an Initial Presentation of Hematologic Disease: Two Cases Reports

Authors

  • Pirunrat Jiaraksuwan Department of Ophthalmology, Medical Education Center, Surin Hospital

Keywords:

bilateral central retinal vein occlusion, hematologic disease

Abstract

Bilateral central retinal vein occlusion (CRVO) is uncommon presentation. The author reported two cases (30-yearold,
73-year-old) of bilateral CRVO. The patients came to hospital with ophthalmic problems which required medical
and laboratory investigations. They were newly diagnosed with hematological disorders. Early treatment of underlying
diseases should be performed to save life and improve visions. The visual prognosis and clinical outcomes depend on
hematologic disease.

References

Song P, Xu Y, Zha M, Zhang Y, Rudan I. Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors. J Global Health. 2019;9(1).

Liu W, Xu L, Jonas JB. Vein occlusion in Chinese subjects. Ophthalmology. 2007;114(9):1795-6.

Upayokin K. Diseases associated with retinal vein occlusion in Lamphun hospital. LPHJ. 2016;12(1):16-22.

Talcott KE, Garg RJ, Garg SJ. Ophthalmic manifestations of leukemia. Curr Opin Ophthalmol. 2016;27(6): 545-51.

Tseng M-Y, Chen Y-C, Lin Y-Y, Chu S-J, Tsai S-H. Simultaneous bilateral central retinal vein occlusion as the initial presentation of acute myeloid leukemia.Am J Med Sci. 2010;339(4):387-9.

Goel N, Pangtey B, Thakar M, Raina UK, Ghosh B. Chronic myeloid leukemia presenting with bilateral central retinal vein occlusion and massive retinal infiltrates. J Am Assoc Pediatr Ophthalmol Strabismus. 2012;16(4):406-8.

Narang S, Gupta P, Sharma A, Sood S, Palta A, Goyal S. Bilateral central retinal vein occlusion as presenting feature of chronic myeloid leukemia. Middle East African J Ophthalmol. 2016;23(3):253.

Uhr JH, Thau A, Chung C, Zhang XC. Rare presentation of bilateral central retinal vein occlusion and leukemic retinopathy in a young adult diagnosed with T-cell acute lymphoblastic leukemia. Cureus. 2020;12(1).

Al-Abdulla NA, Thompson JT, LaBorwit SE. Simul taneous bilateral central retinal vein occlusion associated with anticardiolipin antibodies in leukemia. Am J Ophthalmol. 2001;132(2):266-8.

Savage DG, Szydlo RM, Goldman JM. Clinical features at diagnosis in 430 patients with chronic myeloid leukaemia seen at a referral centre over a 16-year period. Br J Haematol. 1997;96(1):111-6.

Ikezoe T. Pathogenesis of disseminated intravascular coagulation in patients with acute promyelocytic leukemia, and its treatment using recombinant human soluble thrombomodulin. Int J Hematol. 2014;100(1):27-37.

Smith SW, Sato M, Gore SD, Baer MR, Ke X, McNally D, et al. Erythropoiesis-stimulating agents are not associated with increased risk of thrombosis in patients with myelodysplastic syndromes. Haematologica. 2012;97(1):15.

Berry D, Fekrat S. Central retinal vein occlusion in GATA2 deficiency. Retin Cases Brief Rep. 2019;13(2):181-4.

Downloads

Published

2023-03-31