Lynch Syndrome

Authors

  • Chompoonut Achavanuntakul Department of Surgery, Faculty of Medicine, Thammasat University, Thammasat University Hospital, Pathum thani
  • Worawarn Worasawate Department of Surgery, Nopparat Rajathanee Hospital, Bangkok

Keywords:

Lynch Syndrome, HNPCC, Hereditary Non Polyposis Colorectal Cancer, โรคมะเร็งลำไส้ใหญ่และทวารหนัก, โรคมะเร็งซึ่งถ่ายทอดทางพันธุกรรม

Abstract

Colon and rectum cancer is the third common cancer worldwide and second leading course of death from cancer. Lynch Syndrome is the most common hereditary colon cancer. Lynch Syndrome occur from defect of MMR gene and course many cancers such as colon cancer, ovarian cancer, gastric cancer, and brain cancer. This syndrome cannot preventable but can early screening and treatment for better outcome and survival.

This article assembled and summarized up to date holistic document about risk factor, screening tool, diagnosis test, treatment recommendation, chemoprevention, and genetic consultation, that the physicians or surgeons can applied to the patient proper.

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Author Biographies

Chompoonut Achavanuntakul, Department of Surgery, Faculty of Medicine, Thammasat University, Thammasat University Hospital, Pathum thani

 

 

Worawarn Worasawate, Department of Surgery, Nopparat Rajathanee Hospital, Bangkok

 

 

Published

2022-06-22

How to Cite

Achavanuntakul, C., & Worasawate, W. (2022). Lynch Syndrome. Journal of the Association of General Surgeons of Thailand under the Royal of Patronage of HM the King, 7(2), 98–110. Retrieved from https://he02.tci-thaijo.org/index.php/agstjournal/article/view/256796