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Laughter actually has positive emotional effect. However, it could be pathologic when laughter is not related to emotion and occurs independent of a stimulus in the environment. We reported a 7-year-6-month old Thai boy who presented with ‘early giggles’ since the age of 2 months. Despite parental concerns, the symptoms were overlooked until seven years of age, when he developed complex partial seizures. An MRI study of the brain revealed a small ill defined lesion within the tuber cinereum that was compatible with hypothalamic hamartoma.
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