Hirayama’s Disease

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Ekasit Leackong, MD
Kongkiat Kulkantrakorn, MD


Hirayama’s disease, also known as juvenile non-progressive cervical amyotrophy or monomelic amyotrophy is a rare focal motor neuron disease that primarily affects young Asian males (15-25 years old). The À rst case was reported by Hirayama in 1959. The patient often has insidious and slowly progressive weakness, followed by a spontaneous arrest within several years. Even though its etiology has not been clearly identiÀ ed, the hypothesis of dynamically chronic compression of cervical spinal cord was proposed. This is demonstrated by magnetic resonance imaging (MRI) of cervical spine which shows forward displacement of the posterior wall of the lower cervical dural canal. It leads to marked, often asymmetric, Á attening of the lower cervical cord. Early diagnosis is key to successful management. Surgical decompression in some cases and physical therapy are the treatment options.1-3 This is a report of a you

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Leackong E, Kulkantrakorn K. Hirayama’s Disease. BKK Med J [Internet]. 2019 Sep. 28 [cited 2024 Jun. 20];6(1):45. Available from: https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/218619
Case Report


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