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Chronic pancreatitis (CP) is a progressive disease with irreversible changes in the pancreas. Patients commonly present with pain. All therapeutic efforts in CP are directed towards the relief of pain. Endoscopic therapy either endoscopic retrograde pancreatography (ERP) or endoscopic ultrasound (EUS) guided pancreatic drainage, offers pain relief in patients with CP who present with ductal calculi and/or main pancreatic duct strictures with upstream dilation with a high rate of success with low morbidity in properly selected patients.
Interventional Endoscopic ultrasound (EUS) is an emerging technology to provide pancreatic duct drainage to patients when conventional ERP technique fails or in the case of inaccessible pancreatic ducts. Endotherapy should be offered as the first line of therapy in properly selected patients with CP who have failed to respond to medical therapy and require intervention.
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