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We report on a 62-year-old female with a 10-year history of hypertension and of systemic lupus erythematosus with Sjogren’s syndrome for 5 years. Her current visit showed worsening anemia with severe proteinuria and deterioration of renal function. Renal biopsy showed deposition of amyloid A as demonstrated by immunohistochemical staining with amyloid A specific antibody and electron microscopy. Immunofluorescence microscopy revealed deposition of C3, leading to the diagnosis of AA amyloidosis secondary to SLE. The patient received colchicine for one month and she did not follow-up.
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