Pilomatricoma: A Case Report with a Distinctive Histological Presentation and a Literature Review

Main Article Content

Wanlada Sawangarun, DDS
Risa Chaisuparat, DDS, PhD


Pilomatricoma is an uncommon benign neoplasm commonly affecting the head andneck region of the pediatric patient group. This lesion is clinically described as a wellcircumscribed, slow growing, firm mass with normal overlying skin. It is oftenmisdiagnosed clinically and an accurate diagnosis can only be made by histologicalexamination. Histological features of pilomatricoma are generally consistent, characterizedby a biphasic population of ghost cells and basophilic cells arranged in irregular islandsor sheets. Pilomatricoma is best treated by surgical excision and reports of recurrenceare rare. Here, we report a case of pilomatricoma of the cheek in a female Asian childexhibiting a distinctive histological feature and a literature review of relevant informationof the pilomatricoma is discussed


Download data is not yet available.

Article Details

How to Cite
Sawangarun W, Chaisuparat R. Pilomatricoma: A Case Report with a Distinctive Histological Presentation and a Literature Review. BKK Med J [Internet]. 2017 Feb. 20 [cited 2023 Dec. 5];13(1):63. Available from: https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/221799
Case Report


1. Kaddu S, Soyer HP, Hodl S, et al. Morphological stages of pilomatricoma. Am J Dermatopathol 1996;18:333-8.
2. Kaveri H, Punnya A. Pilomatricoma: a dermal analog of calcifying odontogenic cyst. Indian J Dent Res 2008;19:261-3.
3. Lan MY, Lan MC, Ho CY, et al. Pilomatricoma of the head and neck: a retrospective review of 179 cases. Arch Otolaryngol Head Neck Surg 2003;129:1327-30.
4. Agarwal RP, Handler SD, Matthews MR, et al. Pilomatrixoma of the head and neck in children. Otolaryngol Head Neck Surg 2001;125:510-5.
5. Danielson-Cohen A, Lin SJ, Hughes CA, et al. Head and neck pilomatrixoma in children. Arch Otolaryngol Head Neck Surg 2001;127:1481-3.
6. Duflo S, Nicollas R, Roman S, et al. Pilomatrixoma of the head and neck in children: a study of 38 cases and a review of the literature. Arch Otolaryngol Head Neck Surg 1998;124: 1239-42.
7. Yencha MW. Head and neck pilomatricoma in the pediatric age group: a retrospective study and literature review. Int J Pediatr Otorhinolaryngol 2001;57:123-8.
8. Al-Khateeb TH, Hamasha AA. Pilomatricoma of the maxillofacial area in the northern regional Jordanian population: Report of 31 cases. J Oral Maxillofac Surg 2007;65:261-6.
9. Hasson O, Shacham R, Nahlieli O, et al. A firm, bluish mass of the cheek in a 17-month-old child. J Oral Maxillofac Surg 2002;60:301-4.
10. Levy J, Ilsar M, Deckel Y, et al. Eyelid pilomatrixoma: a description of 16 cases and a review of the literature. Surv Ophthalmol 2008;53:526-5.
11. Kim SH, Lee MG, Lee KG. Basal cell carcinoma with matrical differentiation. Yonsei Med J 2003;44:523-5.
12. Carpentieri DF, Qualman SJ, Bowen J, et al. Protocol for the examination of specimens from pediatric and adult patients with osseous and extraosseous ewing sarcoma family of tumors, including peripheral primitive neuroectodermal tumor and ewing sarcoma. Arch Pathol Lab Med 2005;129:866-73.
13. Gorlin RJ, Pindborg JJ, Odont, et al. The calcifying odontogenic cyst--a possible analogue of the cutaneous calcifying epithelioma of Malherbe. An analysis of fifteen cases. Oral Surg Oral Med Oral Pathol 1962;15:1235-43.