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Pilomatricoma is an uncommon benign neoplasm commonly affecting the head andneck region of the pediatric patient group. This lesion is clinically described as a wellcircumscribed, slow growing, firm mass with normal overlying skin. It is oftenmisdiagnosed clinically and an accurate diagnosis can only be made by histologicalexamination. Histological features of pilomatricoma are generally consistent, characterizedby a biphasic population of ghost cells and basophilic cells arranged in irregular islandsor sheets. Pilomatricoma is best treated by surgical excision and reports of recurrenceare rare. Here, we report a case of pilomatricoma of the cheek in a female Asian childexhibiting a distinctive histological feature and a literature review of relevant informationof the pilomatricoma is discussed
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