Evaluation of the Antioxidant Activity, Collagen Synthesis and Stability of Bright and Firm hybrid emulsion I

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Sitthiphon Bunman, MSc
Pannee Chinjarernpan, PhD
Sirawit Stitsmith, MD
Apicha Jabsuwan, MSc
Sanghyun Kim, MSc


OBJECTIVES: The aim of this study was to evaluate antioxidant activity, collagen synthesis, and stability of bright and firm hybrid emulsion I.

MATERIAL AND METHODS: The stability was evaluated by pH test, heating and cooling test, and microbial growth test. The antioxidant activity was evaluated by 2,2′-Diphenyl-1-picrylhydrazyl (DPPH) method, 2,2-Azino-bis-3-ethylbenzothiazoline- 6-sulfonic acid (ABTS) method, and ferric reducing antioxidant power (FRAP) method. Histological analysis was stained with Masson’s trichrome and evaluated for collagen synthesis on days 28.

RESULT: Bright and firm hybrid emulsion I had antioxidant activity and was stable under room temperature. Histological analysis was performed on day 28. Bright and firm hybrid emulsion I increased collagen synthesis when compared with the control group.

CONCLUSION: This study demonstrated that bright and firm hybrid emulsion I has antioxidant effect, increases collagen synthesis and stabilizes under room temperature.


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Bunman S, Chinjarernpan P, Stitsmith S, Jabsuwan A, Kim S. Evaluation of the Antioxidant Activity, Collagen Synthesis and Stability of Bright and Firm hybrid emulsion I. BKK Med J [Internet]. 2019Sep.20 [cited 2020Jul.15];15(2):168. Available from: https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/222824
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