Use of Endobronchial Ultrasound Guided Mediastinal Cryobiopsy in Addition to Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Rapid on Site Evaluation for Evaluation of Enlarged Mediastinal Nodes ( Case series )

Main Article Content

Sawang Saenghirunvattana
Winyou Mitarnun
Chao Saenghirunvattana

Abstract

Endobronchial ultrasound guided transbronchial needle aspiration (EBUS- TBNA) with rapid on site evaluation (ROSE) has been used worldwide in the diagnosis of enlarged mediastinal nodes, with minimally invasive techniques, for many years. With recent advances in the genetic study of cancer, in order to determine the appropriate chemotherapy for cancer, more tissue samples need to be studied, and the amount of tissue obtained via EBUS-TBNA may not be adequate in patients with cancer, lymphoma and sarcoidosis. Recently it has been found that the technique of EBUS-guided mediastinal cryobiopsy (EBUS-MCB) may provide an adequate tissue amount for study with minimal invasiveness and performed safely. We reported 3 cases of enlarged mediastinal nodes, using EBUS-TBNA, and ROSE, and EBUS-MCB in an additional 2 cases. EBUS-MCB provided additional information in 1 case, and confirmation in 1 case. EBUS-MCB is a useful tool to supplement EBUS-TBNA and ROSE in the investigation of enlarged mediastinal nodes.

Article Details

How to Cite
1.
Saenghirunvattana S, Mitarnun W, Saenghirunvattana C. Use of Endobronchial Ultrasound Guided Mediastinal Cryobiopsy in Addition to Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Rapid on Site Evaluation for Evaluation of Enlarged Mediastinal Nodes ( Case series ). BKK Med J [Internet]. 2024 Sep. 30 [cited 2024 Oct. 14];20(2):125. Available from: https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/270647
Section
Speacial Feature

References

M.M. Wahidi, et al. Technical aspects of endobronchial ultrasound guided transbronchial needle aspiration : CHEST 2016 : 149 ; 816-835

G.Labraca, et al. Diagnostic accuracy of endobronchial ultrasound guided transbronchial aspiration in lymphoma ;

a systematic review and meta analysis. Ann Am Thorac Soc 2019 16: 1432-39

J.Zhang et al; Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions Eur Respir J 2021 : 58

Maturu VN ,Prasad VP,Vaddepally C ,et al Endobronchial Ultrasound guided mediastinal lymph nodal cryobiopsy in patients with nondiagnostic/inadquate rapid on site evaluation:A new step in the diagnostic Algorithm . J Bronchology Interv Pulmonol.2024 Jan 1;31(1): 2-12

Poletti V , Petrarulo S et al; EBUS-guided cryobiopsy in the diagnosis of thoracic disorders. Pulmonary Journal , Jan 2024 10.1016

Chalhoub M , Joseph B, Acharya S. A review of endobronchial ultrasound guided transbronchial intranodal forceps biopsy and cryobiopsy. Diagnostics 2024 14 (9),965