Feline Portosystemic Shunts: A Case Report


  • Poonnut Darakamas Prasuarthon Animal Hospital, Faculty of Veterinary Sciences, Mahidol University
  • Panyakamol Chandrasakha Prasuarthon Animal Hospital, Faculty of Veterinary Sciences, Mahidol University
  • Sukanya Maneein Department of Veterinary Clinical Sciences and Public Health, Faculty of Veterinary sciences, Mahidol University
  • Rungrote Osathanon Department of Veterinary Clinical Sciences and Public Health, Faculty of Veterinary sciences, Mahidol University
  • Pasakorn Brikshavana Kaewkarn Animal Hospital
  • Krittin Chuaychoo Prasuarthon Animal Hospital, Faculty of Veterinary Sciences, Mahidol University
  • Namphung Seumanotham Department of Veterinary Clinical Sciences and Public Health, Faculty of Veterinary sciences, Mahidol University


Portosystemic shunts, PSS, Ammonia, Cellophane banding


A 4 kg, 3 year-old, spayed female, Persian cat was presented at Prasu-Arthorn Animal Hospital, Faculty of Veterinary Science, Mahidol University with the clinical sign of ptyalism for the past year. Two days before the visit, the owner reported a behavioral change, circling and obtunded. From the physical examination, all vital signs were normal. Hematological values were within reference interval. However, Serum ammonia and Pre-prandial Post-prandial bile acid were elevated. Thoracic radiographic and abdominal ultrasonographic findings were unremarkable. Computed tomography (CT) result revealed the left gastro-caval shunt with portal hypertension. The cat was diagnosed as feline extrahepatic portosystemic shunt. Surgical excision was applied with cellophane banding. The cat was admitted for post-operative care for 7 days. During the hospitalization, pain assessment was monitored with systolic blood pressure and closely observed the clinical sign of seizure. Moreover, abdominal ultrasonography was performed to monitor ascites and peritonitis. The ammonia and pre-prandial/post -prandial bile acid tests was done on day 1,7 and 120 after surgery which displayed within normal range. The cat did not express ptyalisim or neurological disorders such as seizure after surgery during the observation period more than 120 days. This case report aimed to describe a successful treatment of portosystemic shunt in a cat.


Berent AC, Tobias KM. Portosystemic Vascular Anomalies. Veterinary Clinics of North America: J Small Anim Pract. 2009;39(3):513-41.

Blaxter AC, Holt PE, Pearson GR, Gibbs C, Gruffydd-Jones TJ. Congenital portosystemic shunts in the cat: A report of nine cases. J Small Anim Pract. 1988;29(10):631-45.

Buob S, Johnston AN, Webster CR. Portal hypertension: pathophysiology, diagnosis, and treatment. J Vet Intern Med. 2011;25(2):169-86.

Cabassu J, Seim HB, 3rd, MacPhail CM, Monnet E. Outcomes of cats undergoing surgical attenuation of congenital extrahepatic portosystemic shunts through cellophane banding: 9 cases (2000-2007). J Am Vet Med Assoc. 2011;238(1):89-93.

Carr AP. 42 - Liver. In: Rubin SI, Carr AP, editors. Canine Internal Medicine Secrets. Saint Louis: Mosby; 2007. p. 293-304.

Devriendt N, Serrano G, Paepe D, de Rooster H. Liver function tests in dogs with congenital portosystemic shunts and their potential to determine persistent shunting after surgical attenuation. Vet J. 2020;261:105478.

Dimski DS. Ammonia metabolism and the urea cycle: function and clinical implications. J Vet Intern Med. 1994;8(2):73-8.

Greenhalgh S, Dunning M, McKinley T, Goodfellow M, Kelman K, Freitag T, et al. Comparison of survival after surgical or medical treatment in dogs with a congenital portosystemic shunt. J Am Vet Med Assoc. 2010;236:1215-20.

Havig M, Tobias KM. Outcome of ameroid constrictor occlusion of single congenital extrahepatic portosystemic shunts in cats: 12 cases (1993-2000). J Am Vet Med Assoc. 2002;220(3):337-41.

Hunt GB, Kummeling A, Tisdall PL, Marchevsky AM, Liptak JM, Youmans KR, et al. Outcomes of cellophane banding for congenital portosystemic shunts in 106 dogs and 5 cats. Vet Surg. 2004a;33(1):25-31.

Hunt GB, Culp WT, Mayhew KN, Mayhew P, Steffey MA, Zwingenberger A. Evaluation of in vivo behavior of ameroid ring constrictors in dogs with congenital extrahepatic portosystemic shunts using computed tomography. Vet Surg. 2014b;43(7):834-42.

Isobe K, Matsunaga S, Nakayama H, Uetsuka K. Histopathological characteristics of hepatic lipogranulomas with portosystemic shunt in dogs. J. Vet. Med. Sci. 2008;70(2):133-8.

Joffe MR, Hall E, Tan C, Brunel L. Evaluation of different methods of securing cellophane bands for portosystemic shunt attenuation. Vet Surg. 2019;48(1):42-9.

Lamb CR, Forster-van Hijfte MA, White RN, McEvoy FJ, Rutgers HC. Ultrasonographic diagnosis of congenital portosystemic shunt in 14 cats. J Small Anim Pract. 1996;37(5):205-9.

Lamb CR. Ultrasonography of Portosystemic Shunts in Dogs and Cats. Vet Clin North Am Small Anim Pract. 1998;28(4):725-53.

Leeman JJ, Kim SE, Reese DJ, Risselada M, Ellison GW. Multiple congenital PSS in a dog: case report and literature review. J Am Anim Hosp Assoc. 2013;49(4):281-5.

Lipscomb VJ, Jones HJ, Brockman DJ. Complications and long-term outcomes of the ligation of congenital portosystemic shunts in 49 cats. Vet Rec. 2007;160(14):465-70.

McAlinden AB, Buckley CT, Kirby BM. Biomechanical evaluation of different numbers, sizes and placement configurations of ligaclips required to secure cellophane bands. Vet Surg. 2010;39(1):59-64.

Paepe D, Vermote K, Saunders J, Risselada M, Daminet S. Portosystemic shunts in dogs and cats: Laboratory diagnosis of congenital portosystemic shunts. Vlaams Diergeneeskd. Tijdschr. 2007;76:241-8.

Papamichail M, Pizanias M, Heaton N. Congenital portosystemic venous shunt. Eur J Pediatr. 2018;177(3):285-94.

Ruland K, Fischer A, Hartmann K. Sensitivity and specificity of fasting ammonia and serum bile acids in the diagnosis of portosystemic shunts in dogs and cats. ASVCP. 2009a;39:57-64.

Ruland K, Fischer A, Reese S, Zahn K, Matis U, Hartmann K. Portosystemic shunts in cats-evaluation of six cases and a review of the literature. Berl Munch Tierarztl Wochenschr. 2009b;122(5-6):211-8.

Strickland R, Tivers MS, Fowkes RC, Lipscomb VJ. Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats. Vet Surg. 2021;50(2):303-11.

Sugimoto S, Maeda S, Tsuboi M, Saeki K, Chambers JK, Yonezawa T, et al. Multiple acquired portosystemic shunts secondary to primary hypoplasia of the portal vein in a cat. J Vet Med Sci. 2018;80(6):874-7.

Tillson DM, Winkler JT. Diagnosis and treatment of portosystemic shunts in the cat. Vet Clin North Am Small Anim Pract. 2002;32(4):881-99.

Tivers M, Lipscomb V. Congenital Portosystemic Shunts in Cats: Investigation, diagnosis and stabilisation. J Feline Med Surg. 2011a;13(3):173-84.

Tivers M, Lipscomb V. Congenital Portosystemic Shunts in Cats: Surgical management and prognosis. J Feline Med Surg. 2011b;13(3):185-94.

Tobias KM. Current veterinary therapy. St louis (MO): Saunders Elsevier; 2009.

Valiente P, Trehy M, White R, Nelissen P, Demetriou J, Stanzani G, et al. Complications and outcome of cats with congenital extrahepatic portosystemic shunts treated with thin film: Thirty-four cases (2008-2017). J Vet Intern Med. 2020;34(1):117-24.




How to Cite

Darakamas, P., Chandrasakha, P., Maneein, S. ., Osathanon, R. ., Brikshavana, P. ., Chuaychoo, K. ., & Seumanotham, N. (2022). Feline Portosystemic Shunts: A Case Report. Journal of Applied Animal Science, 15(1), 23–34. Retrieved from https://he02.tci-thaijo.org/index.php/jaas_muvs/article/view/258368



Case report