Predictive Factors of Fertility Quality of Life among Infertile Women
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Abstract
Purpose: To study the level of fertility quality of life and predictive power of education level, family income, duration of infertility, resilience, infertility-related stress, and social support on fertility quality of life among women with infertility.
Design: Predictive correlational study design.
Methods: The sample consisted of 123 women with primary infertility attending the infertile clinic at Siriraj Hospital. The data were collected via the Fertility Quality of Life Questionnaire, Resilience Scale 10, Infertility-related Stress Questionnaire, and the Multidimensional Scale of Perceived Social Support Questionnaire. Data were analyzed using descriptive statistics and multiple linear regression.
Main findings: The findings revealed that education level, family income, duration of infertility, resilience, infertility-related stress, and social support together accounted for 62.5% of the variance explained in the fertility quality of life among infertile women (R2 = .63, F = 32.21, p < .001). Nevertheless, the significant predictors included infertility-related stress (β = - .55, p < .001), resilience (β = .26, p < .001), social support (β = .19, p < .001), and education level (β = .15, p = .015).
Conclusion and recommendations: Infertility-related stress, resilience, social support, and education level affected fertility quality of life among infertile women. Therefore, nurses at an infertility clinic should screen the following predictive factors including infertility-related stress, resilience, social support, and level of education for planning the promotion of the fertility quality of life among infertile women.
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References
Walker MH, Tobler KJ. Female infertility [Internet]. Treasure Island, FL: StatPearls Publishing; 2022 [cite 2025 Feb 3]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556033.
Division of Medical Facilities and Medical Practice, Department of Health Service Support, Ministry of Public Health. Annual report on the provision of assisted reproductive technology services 2023. Nonthaburi: Division of Medical Facilities and Medical Practice; 2024 [cited 2025 Feb 3]. Available from: https://mrd.hss.moph.go.th/mrd1_hss/wp-content/uploads/2024/11/%E0%B8%9B%E0%B8%A3%E0%B8%B0%E0%B8%88%E0%B8%B3%E0%B8%9B%E0%B8%B5-2566.pdf. (in Thai).
Bose S, Roy B, Umesh S. Marital duration, and fertility-related stress as predictors of quality of life: gender differences among primary infertile couples. J Hum Reprod Sci. 2021;14(2):184-90. doi: 10.4103/jhrs.jhrs_233_20.
Wu M-H, Su P-F, Chu W-Y, Huey NG, Lin C-W, Ou H-T, et al. Quality of life and pregnancy outcomes among women undergoing in vitro fertilization treatment: a longitudinal cohort study. J Formos Med Assoc. 2020;119(1 Pt 3):471-9. doi: 10.1016/j.jfma.2019.06.015.
[No authors listed]. The World Health Organization Quality of Life assessment (WHOQOL): development and general psychometric properties. Soc Sci Med. 1998;46(12):1569-85. doi: 10.1016/s0277-9536(98)00009-4.
Wdowiak A, Anusiewicz A, Bakalczuk G, Raczkiewicz D, Janczyk P, Makara-Studzińska M. Assessment of quality of life in infertility treated women in Poland. Int J Environ Res Public Health. 2021;18(8):4275. doi: 10.3390/ijerph18084275.
Karabulut A, Ozkan, S, Oguz N. Predictors of fertility quality of life (FertiQoL) in infertile women: analysis of confounding factors. Eur J Obstet Gynecol Reprod Biol. 2013;170(1):193-7. doi: 10.1016/j.ejogrb.2013.06.029.
Ni Y, Tong C, Huang L, Zhou W, Zhang A. The analysis of fertility quality of life and the influencing factors of patients with repeated implantation failure. Health Qual Life Outcomes. 2021;19(1):32. doi: 10.1186/s12955-021-01666-3.
Kiani Z, Simbar M, Hajian S, Zayeri F, Shahidi M, Saei Ghare Naz M, et al. The prevalence of anxiety symptoms in infertile women: a systematic review and meta-analysis. Fertil Res Pract. 2020;6(7):1-10. doi: 10.1186/s40738-020-00076-1
Song D, Li X, Yang M, Wang N, Zhao Y, Diao S, et al. Fertility quality of life (FertiQoL) among Chinese women undergoing frozen embryo transfer. BMC Womens Health. 2021;21(1):177. doi: 10.1186/s12905-021-01325-1.
Zurlo MC, Cattaneo Della Volta MF, Vallone F. The association between stressful life events and perceived quality of life among women attending infertility treatments: the moderating role of coping strategies and perceived couple’s dyadic adjustment. BMC Public Health. 2019;19(1):1548. doi: 10.1186/s12889-019-7925-4.
Swift A, Reis P, Swanson M. Infertility stress, cortisol, coping, and quality of life in U.S. women who undergo infertility treatments. J Obstet Gynecol Neonatal Nurs. 2021;50(3):275-88. doi: 10.1016/j.jogn.2020.12.004.
Li Y, Zhang X, Shi M, Guo S, Wang L. Resilience acts as a moderator in the relationship between infertility-related stress and fertility quality of life among women with infertility: a cross-sectional study. Health Qual Life Outcomes. 2019;17(1):38. doi: 10.1186/s12955-019-1099-8.
Shin H, Lee J, Kim S-J, Jo M. Associations of symptoms of depression, social support, and quality of life among Korean women who experience infertility. J Obstet Gynecol Neonatal Nurs. 2021;50(6):e1-e12. doi: 10.1016/j.jogn.2021.06.007.
Maria de. Quality of life among men and women diagnosed with infertility in Khyber Pakhtunkhwa. Clin Pract. 2023;20(3):1-11.
Ha J-Y, Ban S-H. Effect of resilience on infertile couples’ quality of life: an actor-partner interdependence model approach. Health Qual Life Outcomes. 2020;18(1):295. doi: 10.1186/s12955-020-01550-6.
Ghorbani M, Hosseini FS, Yunesian M, Keramat A. Dropout of infertility treatments and related factors among infertile couples. Reproductive Health. 2020;17(1):192. doi: 10.1186/s12978-020-01048.
Boivin J, Takefman J, Braverman A. The fertility quality of life (FertiQoL) tool: development and general psychometric properties. Hum Reprod. 2011;26(8):2084-91. doi: 10.1093/humrep/der171.
Connor KM, Davidson JR. Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). Depress Anxiety. 2003;18(2):76-82. doi: 10.1002/da.10113.
Vongsirimas N, Thanoi W, Yobas PK. Evaluating psychometric properties of the Connor–Davidson Resilience Scale (10-Item CD-RISC) among university students in Thailand. Nursing Science Journal of Thailand. 2017;35(3):25-35.
Schmidt L, Holstein BE, Christensen U, Boivin J. Communication and coping as predictors of fertility problem stress: cohort study of 816 participants who did not achieve a delivery after 12 months of fertility treatment. Hum Reprod. 2005;20(11):3248-56. doi: 10.1093/humrep/dei193.
Srichum D, Ratinthorn A, Pungbangkadee R. Factors influencing infertility related stress among women with infertility. Journal of The Royal Thai Army Nurses. 2021;22(3):453-61. (in Thai).
Zimet GD, Dahlem NW, Zimet SG, Farley GK. The multidimensional scale of perceived social support. J Pers Assess. 1988;52(1):30-41. doi: 10.1207/s15327752jpa5201_2.
Wongpakaran T, Wongpakaran N, Sirirak T, Arunpongpaisal S, Zimet G. Confirmatory factor analysis of the revised version of the Thai multidimensional scale of perceived social support among the elderly with depression. Aging Ment Health. 2018;22(9):1143-8. doi: 10.1080/13607863.2017.1339778.
Andrei F, Salvatori P, Cipriani L, Damiano G, Dirodi M, Trombini E, et al. Self-efficacy, coping strategies and quality of life in women and men requiring assisted reproductive technology treatments for anatomical or non-anatomical infertility. Eur J Obstet Gynecol Reprod Biol. 2021;264:241-6. doi: 10.1016/j.ejogrb.2021.07.027.
Ngai FW, Loke AY. Relationships between infertility-related stress, family sense of coherence and quality of life of couples with infertility. Hum Fertil (Camb). 2022;25(3):540-7. doi: 10.1080/14647273.2021.1871781.
Bhamani SS, Zahid N, Zahid W, Farooq S, Sachwani S, Chapman M, et al. Association of depression and resilience with fertility quality of life among patients presenting to the infertility centre for treatment in Karachi, Pakistan. BMC Public Health. 2020;20(1):1607. doi: 10.1186/s12889-020-09706-1.
Yousefzade M, Rezaiee Ahvanuiee M, Dolatshahi B, Mohammad-khani P. Predicting fertility quality of life based on coping strategies, duration and infertility factors. Preventive Care in Nursing and Midwifery Journal. 2017;7(3):17-24.
