Additional Gestational Diabetes Screening in Subsequent Antenatal Care Laboratory Tests at Chonburi Hospital

Abstract

Objective: To evaluate the results of additional gestational diabetes (GDM) screening in subsequent antenatal care (ANC) laboratory tests at Chonburi Hospital.

Material and Method: A prospective descriptive study was conducted at the Antenatal Care Unit, Department of Obstetrics and Gynecology, Chonburi Hospital, Thailand. From October 1, 2008 to December 31, 2009.Glucose challenge tests (50-g GCT) simultaneously with subsequent laboratory tests were performed onpregnant women. All positive subjects based on the 50-g GCT were further evaluated by a diagnostic 100 grams oral glucose tolerance test (100-g OGTT). Data including demographic information, clinical risk factors for GDM, 50-g GCT and 100-g OGTT results were collectedand was analyzed using descriptive statistics.

Results: During the study period, 1,282 pregnant women were enrolled. Mean gestational age was 30.3+2.5 weeks. Most of them did not have clinical risk (979 cases, 76.4%). Rate of abnormal 50-g GCT in subsequent tests was 25.12% (322 cases). Of these, 262 cases received 100-g OGTT and 55(21%) of them had GDM. The estimated rate of GDM cases in the non-risk group was 5%. In clinical risk factor groups, the estimated rate of GDM cases in the non-prior test and prior negative tests was 7.4% and 3.9%, respectively. The approximate prevalence of GDM in our populations was 5.1%.

Conclusion: Performing the 50-g GCT simultaneously with subsequent ANC laboratory tests appeared to be feasible and helpful to detect GDM in pregnant women.