Maternal and Neonatal Outcomes in Pre-eclampsia and Normotensive Pregnancies

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Ussanee Sangkomkamhang
Malinee Laopaiboon
Pisake Lumbiganon


Objective: To compare the maternal and neonatal outcomes of pregnancies with pre-eclampsia to those with normotensive.

Materials and Methods: Cases were defined as pregnancies with pre-eclampsia who delivered between January 1st, 2009 and December 31st, 2009 at Khon Kaen Hospital and were compared

with normal blood pressure with a ratio of 1:1 match for age and date of delivery.

The information of maternal and neonatal outcomes was reviewed from the medical and delivery

records. Adjusted odds ratio with 95% confidence intervals were used to evaluate the effect of


Results: There were 302 cases in the study which half of them were pre-eclampsia and the others were normotensive pregnancies. Maternal and neonatal morbidities were significantly higher in pre-eclampsia pregnancies. Pre-eclampsia increases the risk of vaginal operative delivery (adjusted OR 2.6, 95% CI 1.1- 5.9), cesarean section (adjusted OR 1.8, 95% CI 1.1- 3.0), low birth weight (< 2,500 g) (adjusted OR 2.9, 95% CI 1.4- 5.8), and birth asphyxia (adjusted OR 5.3, 95% CI 1.1-

25.1). The most common indication for cesarean section was fetal distress. There were

eight neonatal deaths. The causes of death were respiratory distress syndrome, sepsis and

very low birth weight.

Conclusion: Pre-eclampsia significantly increased the risk of adverse maternal and neonatal



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Article Details

Original Article
Author Biographies

Ussanee Sangkomkamhang, Department of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen.

Malinee Laopaiboon, Department of Biostatistics and Demography, Faculty of Public Health, Khon Kaen University, Khon Kaen.

Pisake Lumbiganon, Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen.