Prevalence of osteoporosis in postmenopausal women at Srinagarind Hospital, Khon Kaen University

Abstract

Objective: To determine the prevalence of osteoporosis in postmenopausal women

Materials and Methods: Retrospectively reviewed medical records of postmenopausal women who attended the menopause clinic during January 2002 to May 2008. All natural postmenopausal women who underwent the bone mineral density (BMD) measurement by Dual-energy X-ray absorptiometry (GE Lunar Prodigy, Japanese software) were included to the study. Osteoporosis was diagnosed by the World Health Organization criteria; BMD value that equal or more than 2.5 standard deviation (SD) below the young adult mean. The exclusion criteria were premature menopause, perimenopause, induced menopause by hysterectomy, bilateral oophorectomy, radiotherapy and chemotherapy and other diseases or medications that affect BMD.

Results: Among 245 postmenopausal women, the mean age of these participants was 55.1±5.2 years, mean duration after menopause was 5.9±4.8 years, mean body weight was 57.8±9.1 kg and mean body mass index (BMI) was 24.5±3.5 kg/m². The prevalence of osteoporosis by utilizing the Japanese BMD cutoff value at the femoral neck (FN) and the lumbar spines (L1-L4) were 1.6% and 10.6%, respectively. When using the Thai BMD cutoff value, the prevalence of osteoporosis was lower than using the Japanese BMD reference (0% for FN and 0.8% for L1-L4). For stratified prevalence estimated according to age group and duration after menopause, the prevalence of osteoporosis was increased with advanced age and duration after menopause for both femoral neck and lumbar spines.

Conclusion: The prevalence of osteoporosis at the femoral neck (1.6%) was fewer than the lumbar spines (10.6%). The prevalence of osteoporosis was increased with advanced age and duration after menopause.