Knowledge, attitudes, and intention to receive pertussis vaccine in pregnant women attending the antenatal care clinic, King Chulalongkorn Memorial Hospital

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Atist Ratanasaengsuang
Wiraporn Theerawut
Surasith Chaithongwongwatthana


Objectives: Although pertussis vaccination in pregnancy to protect young infants is recommended, the vaccine coverage among Thai pregnant women remains suboptimal. This study aimed to determine the proportion of women intending to receive the pertussis vaccine during the current pregnancy.
Materials and Methods: A cross-sectional descriptive study was conducted in Thai pregnant women attending the antenatal care clinic at King Chulalongkorn Memorial Hospital from March to August 2020. A self-administered questionnaire was used to obtain information from participants regarding knowledge, attitudes, and intention to receive pertussis vaccine during pregnancy. Logistic regression analysis was used to determine factors associated with maternal intention.
Results: A total of 387 pregnant women completed the questionnaire. The mean score of knowledge about pertussis and the vaccine was 11.8 ± 2.1 out of 20. Most of the participants had favorable attitudes on pertussis vaccination during pregnancy period. Intention to receive pertussis vaccination during pregnancy was reported in 45.5% (95% confidence interval 40.5% to 50.4%) of women. This proportion would be improved to be 81.9% if their doctors had recommended the vaccine and reassured them about fetal safety. The important influencers on the decision to vaccinate during pregnancy included their doctors (51.0%) and husbands (20.3%). Intention to receive pertussis vaccination during pregnancy would have increased if the participants had known the disease (adjusted odds ratio (OR) 1.74, 95% confidence interval (CI) 1.08 to 2.79) and belived that pertussis vaccination during pregnancy was safe (adjusted OR 2.03, 95% CI 1.20 to 3.43).
Conclusion: Almost half of the pregnant women intended to receive the pertussis vaccine during pregnancy. To improve vaccination coverage among pregnant women, the disease and safety of pertussis vaccine should be emphasized.


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