Postoperative Adjuvant Chemotherapy for High Risk Carcinoma of Cervix Stage 1b

Abstract

Objective To assess rate of recurrence, overall survival rates in relatively high risk  invasive cervical cancer of FIGO stage | patients who received adjuvant oral chemotherapy after standard radical hysterectomy.

Population Invasive cervical cancer of FIGO stage 1 patients from 1985 to 1998, whose patho logical report were categorized to be 'relatively high risk.

Result The evaluable patients included 43 cases. The study revealed 2 recurrent cases (4.6%) with 95% overall 5-year survival time.

Conclusion Postoperative adjuvant oral chemotherapy of 5-Fluorouracil and Mitomicin-C in 'relatively' high risk cervical cancer stage patients is satisfactory in terms of recurrent rate and overall 5-year survival time.