Chorioamnionitis in King Chulalongkorn Memorial Hospital: A five-year review

Abstract

Objective By means of hospital-based data covering five years, we sought to evaluate the incidence, cause, maternal and neonatal outcomes of chorioamnionitis.

Materials and Methods From the obstetric chart records of all deliveries at King Chulalongkorn Memorial Hospital ,Bangkok, between January 1, 1994 and December 31, 1998, we identified all deliveries diagnosed as chorioamnionitis, calculated the incidence rates and identified the cause of chorioamnionitis, as well as maternal and neonatal consequences.

Results There were 151 cases of chorioamnionitis occurring during the study period, giving an incidence of 2.4/1000 deliveries. Most of the cases (49%) occurred in premature rupture of membranes. Cesarean section rate in these cases amounted to 86/151 (57%) and maternal morbidity to 10/151 (6.6%), whereas neonatal morbidity and mortality were 63/151(41.7%) and 4/151(2.6%), respectively.

Conclusion Most of the cases diagnosed as chorioamnionitis at King Chulalongkorn Memorial Hospital occurred in premature rupture of membranes. Maternal morbidity was low whereas neonatal morbidity was high. Improved strategies for management of premature rupture of membranes may reduce the incidence of chorioamnionitis and neonatal morbidity.