Effects on Lipid and Carbohydrate Metabolism and Bone Mineral Density in Acceptors Using Depot Medroxyprogesterone Actetate use as a Contraceptive

Abstract

Depot medroxyprogesterone acetate (DMPA) is an aqueous suspension of 17- acetoxy-6 methyl progestin administered by intramuscular injection for long-term contraception.(1) In Thailand, National Family Planning Program (NFPP) has introduced DMPA to use as a contraceptive since 1970.2) DMPA is also used in many developed and developing countries. (1) However, it is recently being approved for use in the United State and is widely being accepted by women and by their physicians. (3) Although DMPA is widely used around the world, clinical questions have arisen regarding the non-contraceptive risks and benefits. Many researchers have investigated its effects on lipid and carbohydrate metabolism as well as bone mineral density.