Malignant Lipid Cell Tumor of The Ovary

Abstract

Lipid (steroid) cell tumors of the ovary are one of the rarest forms of ovarian neoplasm, account for less than 0.1% of all ovarian neoplasms. A 66-year-old Thai woman with pelvic mass was diagnosed as malignant lipid (steroid) cell tumor of the right ovary. The right ovarian mass weighed 850 gm and measured 15x15x10 cm. The tumor composed of two cell types arranged in clusters and groups as organoid pattern intermingled with delicated fibrovascular stroma. One cell type was polygonal, contained eosinophilic and slightly granular cytoplasm. The other cell type was larger, with abundant, vacuolated, often spongy cytoplasm. Foci of necrosis and hemorrhage were observed. The histopathological evidence of metastasis to omentum, wall of sigmoid colon and mesentery of caecum was compatible with malignant lipid cell tumor of the ovary. The patient received 6 courses of chemotherapy and loss to follow-up 7 months after the main operation.