Endometrial Carcinoma : Surgical Staging and Survival Analysis

Abstract

Objective To determine the five year survival rate according to the FIGO surgical staging system and to analyze the significance of prognostic factors.

Subjects and methods 84 patients with endometrial carcinoma who underwent surgical exploration between 1 January 1988 and 31 December 1992 were enrolled. The Kaplan – Meier method for estimation of survival time and univariate analysis was used. The Log rank was used for comparing factors. In the multivariate analysis, Cox's proportional Hazard model was also used.

Results Five-year survival rate 93%, 75%, 42% and 0% in surgical 1,11,111 and IV respectively. Age, histologic grade, depth of invasion, cervical invasion, adnexal metastasis, lymph node metastasis all correlated to survival in the univariate analysis. In the multivariate study, only depth of invasion was statistically significant correlated to survival.

Conclusion Surgical staging correlates to survival. The outcome of early stage compared favourably with the previous published reports.