Management of Patients with Positive Margins after Cervical Conization: A Review

Abstract

Cervical conization in the evaluation and treat ment of microinvasive (MIC) or cervical intraepithelial neoplasia (CIN) has been well-established procedure. There is still some problems in the management of cases with positive resection margin of the conization specimen. This review will be on this issue dividing according to the histology of conization specimens, i.e. MIC, CIN, and adenocarcinoma in situ (AIS) respec tively. With invasive disease, the management is well defined and will not be discussed here.