Adjuvant Chemotherapy for Stage 1 Uterine Sarcoma

Abstract

Objective To ascertain the long term outcome for women with stage uterine sarcoma.

Results All of the patients after receiving complete surgery were given adjuvant treatment either chemotherapy or radiation. A follow up period of 60-110 months after surgery was done in all cases. Four cases who received adjuvant radiation therapy all developed recurrence within 18 months after radiation therapy. Another 12 cases were given combined chemotherapeutic drugs of cisplatin, Adriamycin and Cyclophosphamide, 11 out of 12 cases are alive with no evidence of disease at present while only one patient developed recurrence at 28 months.

Conclusion The study supports that adjuvant chemotherapy could decrease recurrent rate and prolong survival time in this group of patients.