A Study of the Role of Vaso-Active Prostaglandins (PGI, and TXA,)in Pathophysiological Changes in Pre Eclampsia

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Published: Jul 1, 1993
Keywords:
prostaglandins pathophysiological changes pre-eclampsia

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Malee Juengjaroen
Department of Microbiology, Faculty of Science, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Athiwat Thaworn
Department of Microbiology, Faculty of Science, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Sirikul Chotewuttakorn
Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Abstract

The plasma levels of 6-keto-PGF, and TXB, were assessed by RIA in 7 severe and 19 mild pre-eclampsia (PE). These levels were compared with the levels in 9 normal pregnancies (NP), both antepartum and postpartum. It was found that the levels of 6-keto-PGF, TXB, in mild and severe pre-eclampsia were 578.9 + 26.9, 43.3 16.5 and 517.6 + 76.6, 26.8 + 5.0 pg/ml while in normal pregnancy were only 458.4 + 36.8, 18.6 + 2.2 pg/ml respectively. However, they did not show any significant difference. (Thai J Obstet Gynaecol 1993;5: 63-66.) 

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Juengjaroen, M.; Thaworn, A.; Chotewuttakorn, S. A Study of the Role of Vaso-Active Prostaglandins (PGI, and TXA,)in Pathophysiological Changes in Pre Eclampsia. Thai J Obstet Gynaecol 1993, 5, 63-66.
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VOL. 5, NO. 2: (July - December 1993)
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Original Article
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