Menopausal Symptomatology and Hormonal Correlation

Abstract

To assess the correlation between climacteric symptoms and objective measurement of hormonal changes in women suffering from natural and surgical menopause, we conducted measurement of serum concentration of follicle stimu lating hormone (FSH), luteinizing hormone (LH), and estradiol (E.) by radioimmunoassay on 48 Thai women attending the menopausal clinic at the De partment of Obstetrics and Gynaecology, Chulalongkorn Hospital. When comparing the hormonal levels with modified estrogen-deficiency-symptom scoring system, using correlation and regression analysis, the results showed that there was no statistical correlation between hormonal levels (neither FSH, LH nor E) with to tal symptomatological scores. However, when comparing each hormonal profile with detailed a symptom scoring system, the analysis revealed that there was positive correlation between FSH and sexual symptom scores such as less sex drive, less sex feeling, dry vagina and dyspareunia (r = 0.392). (Thai J obstet Gynaecol 1993;4:129-133.)