Serum Levels of Hormone Profiles and Urinary Excre tion of Calcium in Premenopausal and Postmenopausal Women in Taiwan

Abstract

Serum concentrations of FSH, LH, and estradiol, and urinary excretion of calcium were assessed in 20 premenopausal women and 48 postmenopausal women. FSH, LH and estradiol were measured by immunoradiometric assays (IRMA). Urinary calcium (Ca) levels were measured by atomic absorption method, and creatinine (Cr) by Jeffe reaction. The mean concentrations of FSH and LH in postmenopausal women were 79.4 mlUlml and 23.9 mlUlml, which were signifi cantly higher than 4.6 and 5.7 mlU/ml in premenopausal women, respectively. On the other hand, the mean concentration of estradiol in postmenopausal women was 11 pg/ml, which was much lower than of 122 pg/ml in premenopausal women. The mean CalCr molar ratio in postmenopausal women was 0.232, whcih was signifi cantly higher than that of 0.143 in premenopausal women. In conclusion, lower serum concentration of circulating estradiol is one of the possible factors for the increased excretion of calcium and osteoporosis in postmenopausal women. (Thai J Obstet Gynaecol 1991;3:1-5.)