Development of an In Vitro Fertilization and Embryo Transfer Programme : Preliminary Experience

Abstract

From October 1986 to August 1988, a total of 256 cases of infertile women with ages ranging from 26 to 42 years were admitted for the IVF & ET programme. Bilateral tubal occlusion and pelvic endometriosis were the most com mon indications. A combination of clomiphene citrate and hMG (211 cases) or hMG alone (45 cases) were used for superovulation. The average estradiol levels on the day of hCG administration was 1738 † 761 pg/ml. Oocytes were retrieved by either laparoscopy (78 cases) or vaginal ultrasound guidance (178 cases). One hundred and five cases were cancelled (41%) due to poor response and premature LH surge. A total of 542 oocytes were collected and 312 oocytes were fertilized giving a fertilized rate of 57.5%. Embryos at 2 or 4 cells stage were transfered in 151 cases chemical and clinical pregnancies were diagnosed in 30 cases. (Thai J Obstet Gynaecol 1991;2:1-6.)